Introduction：Basic information about CAS 137319-34-7|Dehydroeffusol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Dehydroeffusol |
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| CAS Number | 137319-34-7 | Molecular Weight | 250.29200 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C17H14O2 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Dehydro Effusol |
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| Synonym | More Synonyms |
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Dehydroeffusol BiologicalActivity
| Description | Dehydroeffusol is a phenanthrene from medicinal herb Juncus effuses. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. It shows very low toxicity[1][2]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer |
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| In Vitro | Dehydroeffusol suppresses the expression of vasculogenic mimicry key gene VE-cadherin[2]. Dehydroeffusol decreases the MMP2 expression and activity in gastric cancer cells[2]. |
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| References | [1]. Zhang B, et al. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. Biochem Pharmacol. 2016 Mar 15;104:8-18. [2]. Liu W, et al. Dehydroeffusol effectively inhibits human gastric cancer cell-mediated vasculogenic mimicry with low toxicity. Toxicol Appl Pharmacol. 2015 Sep 1;287(2):98-110. |
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Chemical & Physical Properties
| Molecular Formula | C17H14O2 |
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| Molecular Weight | 250.29200 |
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| Exact Mass | 250.09900 |
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| PSA | 40.46000 |
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| LogP | 4.35560 |
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| InChIKey | GSSPKCPIRDPBQE-UHFFFAOYSA-N |
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| SMILES | C=Cc1cc(O)cc2ccc3c(C)c(O)ccc3c12 |
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Synonyms
| 5-ethenyl-1-methylphenanthrene-2,7-diol |
| 5-Ethenyl-1-methyl-2,7-phenanthrenediol |
| Dehydroeffusol |
