Introduction：Basic information about CAS 130727-41-2|Thiol-C9-PEG4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Thiol-C9-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target
PEGs
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Chemical & Physical Properties
Density
0.995 g/mL at 25ºC
Boiling Point
446.5ºC at 760 mmHg
Molecular Formula
C17H36O4S
Molecular Weight
336.53000
Flash Point
>110ºC
Exact Mass
336.23300
PSA
86.72000
LogP
3.46920
Vapour Pressure
7.55E-10mmHg at 25°C
Index of Refraction
n 20/D 1.476
InChIKey
FASSFROSROBIBE-UHFFFAOYSA-N
SMILES
OCCOCCOCCOCCCCCCCCCCCS
Storage condition
Refrigerator, Under Inert Atmosphere
Safety Information
Personal Protective Equipment
Eyeshields;Gloves
RIDADR
UN 3334
HS Code
2930909090
Customs
HS Code
2930909090
Summary
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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