Introduction：Basic information about CAS 16915-70-1|Nifursol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Nifursol |
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| CAS Number | 16915-70-1 | Molecular Weight | 365.21200 |
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| Density | 1.87 g/cm3 | Boiling Point | / |
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| Molecular Formula | C12H7N5O9 | Melting Point | 215-220ºC (dec.) |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2-hydroxy-3,5-dinitro-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]benzamide |
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| Synonym | More Synonyms |
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Nifursol BiologicalActivity
| Description | Nifursol is a nitrofuran antibiotic which inhibits the growth of Histomonas meleagridis but is not lethal to the flagellated protozoan. Target: AntibacterialNifursol can be analyzed and detected in tissues using intact 3,5-dinitrosalicylic acid hydrazide side chains along with electron-capture GC, spectrophotometric detection, and HPLC with ultraviolet light detection. In tissues, it has been observed that Nifursol is tightly bound to proteins and requires basic solutions such as ammonia to break the bonds between the two. |
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| Related Catalog | Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>Infection |
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Chemical & Physical Properties
| Density | 1.87 g/cm3 |
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| Melting Point | 215-220ºC (dec.) |
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| Molecular Formula | C12H7N5O9 |
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| Molecular Weight | 365.21200 |
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| Exact Mass | 365.02400 |
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| PSA | 212.29000 |
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| LogP | 3.43420 |
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| Index of Refraction | 1.742 |
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| InChIKey | XXUXXCZCUGIGPP-UHFFFAOYSA-N |
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| SMILES | O=C(NN=Cc1ccc([N+](=O)[O-])o1)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1O |
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| Storage condition | Refrigerator, Under Inert Atmosphere |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- VO2980000
- CHEMICAL NAME :
- Salicylic acid, 3,5-dinitro-(5-nitrofurfurylidene)hydrazide
- CAS REGISTRY NUMBER :
- 16915-70-1
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C12-H7-N5-O9
- MOLECULAR WEIGHT :
- 365.24
- WISWESSER LINE NOTATION :
- T5OJ BNW E1UNMVR BQ CNW ENW
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 12,371,1969
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - chicken
- DOSE/DURATION :
- 10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 12,371,1969
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Safety Information
Customs
| HS Code | 2932190090 |
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| Summary | 2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |
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Synonyms
| MFCD00377430 |
| Salfuride |
| NIFURSOL |
| Nifursolum [INN-Latin] |
| Histomon |
| EINECS 240-963-6 |
| Nifursolo [DCIT] |
| Sulfuride |
