Introduction：Basic information about CAS 6149-41-3|Methyl 3-hydroxypropanoate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Methyl 3-hydroxypropanoate |
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| CAS Number | 6149-41-3 | Molecular Weight | 104.104 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 180.5±0.0 °C at 760 mmHg |
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| Molecular Formula | C4H8O3 | Melting Point | / |
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| MSDS | / | Flash Point | 72.6±12.6 °C |
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Names
| Name | Methyl 3-Hydroxypropanoate |
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| Synonym | More Synonyms |
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Methyl 3-hydroxypropanoate BiologicalActivity
| Description | Methyl 3-hydroxypropanoate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | Alkyl/ether |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 180.5±0.0 °C at 760 mmHg |
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| Molecular Formula | C4H8O3 |
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| Molecular Weight | 104.104 |
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| Flash Point | 72.6±12.6 °C |
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| Exact Mass | 104.047340 |
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| PSA | 46.53000 |
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| LogP | -0.90 |
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| Vapour Pressure | 0.3±0.7 mmHg at 25°C |
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| Index of Refraction | 1.414 |
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| InChIKey | RVGLEPQPVDUSOJ-UHFFFAOYSA-N |
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| SMILES | COC(=O)CCO |
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Safety Information
Customs
| HS Code | 2918199090 |
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| Summary | 2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
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Synonyms
| Methyl 3-hydroxypropanoate |
| Propanoic acid, 3-hydroxy-, methyl ester |
| methyl 3-hydroxypropionate |
