CAS 137881-27-7|INH2BP

Introduction:Basic information about CAS 137881-27-7|INH2BP, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameINH2BP
CAS Number137881-27-7Molecular Weight287.05400
Density2.029g/cm3Boiling Point437.6ºC at 760mmHg
Molecular FormulaC9H6INO2Melting Point/
MSDSChineseUSAFlash Point218.4ºC
Symbol
GHS07
Signal WordWarning

Names

Name6-amino-5-iodochromen-2-one
SynonymMore Synonyms

Chemical & Physical Properties

Density2.029g/cm3
Boiling Point437.6ºC at 760mmHg
Molecular FormulaC9H6INO2
Molecular Weight287.05400
Flash Point218.4ºC
Exact Mass286.94400
PSA56.23000
LogP2.56100
Vapour Pressure7.4E-08mmHg at 25°C
Index of Refraction1.737
InChIKeyWWRAFPGUBABZSD-UHFFFAOYSA-N
SMILESNc1ccc2oc(=O)ccc2c1I

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH315-H319-H335
Precautionary StatementsP261-P305 + P351 + P338
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXi
Risk PhrasesR36/37/38
Safety PhrasesS26-S36
RIDADRNONH for all modes of transport

Articles14

More Articles
The Protective Effect of INH2BP, a Novel PARP Inhibitor 5-Iodo-6-Amino-1,2-Benzopyrone, Against Hydrogen Peroxide-Induced Apoptosis Through ERK and p38 MAPK in H9c2 Cells.

Pharmacology 96 , 259-70, (2015)

INH2BP (5-iodo-6-amino-1,2-benzopyrone), a poly-ADP ribose polymerase inhibitor, has been shown to possess anti-cancer, anti-viral, and anti-inflammation properties. The aim of this study was to inves...

4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase.

Arthritis. Res. Ther. 10 , R107, (2008)

4-Hydroxynonenal (HNE) is one of the most abundant and reactive aldehydes of lipid peroxidation products and exerts various effects on intracellular and extracellular signalling cascades. We have prev...

Dichloroacetate enhances apoptotic cell death via oxidative damage and attenuates lactate production in metformin-treated breast cancer cells.

Breast Cancer Res. Treat. 147(3) , 539-50, (2014)

The unique metabolism of breast cancer cells provides interest in exploiting this phenomenon therapeutically. Metformin, a promising breast cancer therapeutic, targets complex I of the electron transp...

Synonyms

5-Iabp
INH2BP
2H-1-Benzopyran-2-one,6-amino-5-iodo
PARP Inhibitor II,INH2BP
5-Iodo-6-amino-1,2-benzopyrone
MFCD00912555
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