Introduction：Basic information about CAS 36099-95-3|G3335, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | G3335 |
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| CAS Number | 36099-95-3 | Molecular Weight | 333.33900 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C16H19N3O5 | Melting Point | / |
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| MSDS | USA | Flash Point | / |
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Names
| Name | 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid |
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| Synonym | More Synonyms |
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G3335 BiologicalActivity
| Description | H-Trp-Glu-OH is a selective, reversible and cell-permeable PPARγ with a Kd of ~8 µM. H-Trp-Glu-OH might be developed as a possible lead compound in diabetes research[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>PPARResearch Areas >>Metabolic Disease |
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| Target | PPARγ:8 μM (Kd) |
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| References | [1]. Ye F, et al. The dipeptide H-Trp-Glu-OH shows highly antagonistic activity against PPARgamma: bioassay with molecular modeling simulation. Chembiochem. 2006 Jan;7(1):74-82. |
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Chemical & Physical Properties
| Molecular Formula | C16H19N3O5 |
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| Molecular Weight | 333.33900 |
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| Exact Mass | 333.13200 |
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| PSA | 145.51000 |
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| LogP | 1.56310 |
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| InChIKey | PWIQCLSQVQBOQV-AAEUAGOBSA-N |
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| SMILES | NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCC(=O)O)C(=O)O |
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| Storage condition | -20℃ |
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Safety Information
| RIDADR | NONH for all modes of transport |
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| HS Code | 2933990090 |
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Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| PPARgamma Antagonist III,G3335 |
| IN1159 |
| TRP-GLU |
| tryptophylglutamic acid |
| L-tryptophyl-L-glutamic acid |
| H-Trp-Glu-OH |
| PPARg Antagonist III,G3335 |
