CAS 65604-80-0|Ophiopogonin D'

Introduction：Basic information about CAS 65604-80-0|Ophiopogonin D', including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Ophiopogonin D' BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Ophiopogonin D'
CAS Number	65604-80-0	Molecular Weight	855.017
Density	1.4±0.1 g/cm3	Boiling Point	/
Molecular Formula	C₄₄H₇₀O₁₆	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	(3β,25R)-Spirost-5-en-3-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)]-β-D-glucopyranoside
Synonym	More Synonyms

Ophiopogonin D' BiologicalActivity

Description	Ophiopogonin D', isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin D' shows cytotoxic activity against two human tumor cell lines MG-63 and SNU387 with IC50s of 3.09 μM and 3.63 μM, respectively[1]. Ophiopogonin D' activates SIRT1 in a dose-dependent manner[2].
Related Catalog	Signaling Pathways >>Epigenetics >>SirtuinResearch Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Sirtuin
Target	SIRT1
References	[1]. Wang L , et al. Homo-aro-cholestane, furostane and spirostane saponins from the tubers of Ophiopogonjaponicus. Phytochemistry. 2017 Apr;136:125-132. [2]. Wang Y, et al. Specific Turn-On Fluorescent Probe with Aggregation-Induced EmissionCharacteristics for SIRT1 Modulator Screening and Living-Cell Imaging. Anal Chem. 2015;87(10):5046-9.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Molecular Formula	C₄₄H₇₀O₁₆
Molecular Weight	855.017
Exact Mass	854.466370
PSA	235.68000
LogP	6.69
Index of Refraction	1.618
InChIKey	DQYACEDUQHWXQZ-QOYNBSPSSA-N
SMILES	CC1CCC2(OC1)OC1CC3C4CC=C5CC(OC6OC(CO)C(O)C(OC7OCC(O)C(O)C7O)C6OC6OC(C)C(O)C(O)C6O)CCC5(C)C4CCC3(C)C1C2C
Storage condition	2-8°C

Synonyms

(3β,25R)-Spirost-5-en-3-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)]-β-D-glucopyranoside

Desacetylophiopogonin B'

Ophiopogonin D`

β-D-glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[β-D-xylopyranosyl-(1->;3)]-

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