CAS 39160-70-8|Amino-PEG6-alcohol

Introduction:Basic information about CAS 39160-70-8|Amino-PEG6-alcohol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameAmino-PEG6-alcohol
CAS Number39160-70-8Molecular Weight281.346
Density1.1±0.1 g/cm3Boiling Point388.0±37.0 °C at 760 mmHg
Molecular FormulaC12H27NO6Melting Point/
MSDS/Flash Point188.5±26.5 °C

Names

Name1-Aminohexaethylene Glycol
SynonymMore Synonyms

Amino-PEG6-alcohol BiologicalActivity

DescriptionAmino-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker
Target

Cleavable

In VitroADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Yong Zu Kim, et al. Antibody-drug conjugates comprising branched linkers and methods related thereto. WO2017089895A1.

Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point388.0±37.0 °C at 760 mmHg
Molecular FormulaC12H27NO6
Molecular Weight281.346
Flash Point188.5±26.5 °C
Exact Mass281.183838
PSA92.40000
LogP-2.80
Vapour Pressure0.0±2.0 mmHg at 25°C
Index of Refraction1.463
InChIKeyICUIZKMGHRMMDZ-UHFFFAOYSA-N
SMILESNCCOCCOCCOCCOCCOCCO
Storage condition2-8°C

Synonyms

3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-amino-
17-Amino-3,6,9,12,15-pentaoxaheptadecan-1-ol
2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Amino-PEG6-alcohol
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