Introduction：Basic information about CAS 3613-73-8|Latrepirdine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Latrepirdine |
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| CAS Number | 3613-73-8 | Molecular Weight | 319.443 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 505.7±50.0 °C at 760 mmHg |
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| Molecular Formula | C21H25N3 | Melting Point | 115-116 °C |
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| MSDS | / | Flash Point | 259.7±30.1 °C |
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Names
| Name | 2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 505.7±50.0 °C at 760 mmHg |
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| Melting Point | 115-116 °C |
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| Molecular Formula | C21H25N3 |
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| Molecular Weight | 319.443 |
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| Flash Point | 259.7±30.1 °C |
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| Exact Mass | 319.204834 |
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| PSA | 21.06000 |
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| LogP | 3.96 |
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| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
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| Index of Refraction | 1.629 |
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| InChIKey | JNODQFNWMXFMEV-UHFFFAOYSA-N |
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| SMILES | Cc1ccc2c(c1)c1c(n2CCc2ccc(C)nc2)CCN(C)C1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- UV0625000
- CHEMICAL NAME :
- 1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2,8-dimethyl-5-(2-(6-methyl-3-pyri dyl)ethyl)-
- CAS REGISTRY NUMBER :
- 3613-73-8
- BEILSTEIN REFERENCE NO. :
- 0622478
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C21-H25-N3
- MOLECULAR WEIGHT :
- 319.49
- WISWESSER LINE NOTATION :
- T B656 DN HNTT&J D1 L1 H2- ET6NJ B1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 356 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 46(5),90,1983
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 178 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 31,105,1968 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1500 mg/kg
- SEX/DURATION :
- female 8-13 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 48(6),89,1985
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Safety Information
Synonyms
| 9-(2-(2-Methyl-5-pyridyl)ethyl)-3,6-dimethyl-1,2,3,4-tetrahydro-γ-carboline |
| 2,8-Dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole |
| Dimebolin |
| Dimebon |
| 1H-Pyrido[4,3-b]indole, 2,3,4,5-tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]- |
| aka latrepiridine |
| Dimebone |
| Latrepirdine |
| Dimeboline |
| 2,8-Dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole |
| 2,8-Dimethyl-5-[2-(6-methyl-pyridin-3-yl)-ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole |
| Preparation 84 |
