CAS 3973-18-0|Propynol Ethoxylate

Introduction：Basic information about CAS 3973-18-0|Propynol Ethoxylate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Propynol Ethoxylate BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Propynol Ethoxylate
CAS Number	3973-18-0	Molecular Weight	100.116
Density	1.0±0.1 g/cm3	Boiling Point	168.7±15.0 °C at 760 mmHg
Molecular Formula	C₅H₈O₂	Melting Point	/
MSDS	/	Flash Point	68.9±14.6 °C

Names

Name	Propynol Ethoxylate
Synonym	More Synonyms

Propynol Ethoxylate BiologicalActivity

Description	Propynol Ethoxylate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

Density	1.0±0.1 g/cm3
Boiling Point	168.7±15.0 °C at 760 mmHg
Molecular Formula	C₅H₈O₂
Molecular Weight	100.116
Flash Point	68.9±14.6 °C
Exact Mass	100.052429
PSA	29.46000
LogP	-0.25
Vapour Pressure	0.5±0.7 mmHg at 25°C
Index of Refraction	1.446
InChIKey	GHGCQQRMJCSIBQ-UHFFFAOYSA-N
SMILES	C#CCOCCO
Storage condition	-20°C

Safety Information

Hazard Codes	Xi
Risk Phrases	36
Safety Phrases	26

Synonyms

MFCD06411441

EINECS 223-601-1

2-(2-Propyn-1-yloxy)ethanol

Propynol ethoxylate

Ethanol, 2-(2-propyn-1-yloxy)-

2-(Prop-2-yn-1-yloxy)ethanol

PME

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