CAS 92-36-4|4-(6-Methyl-2-benzothiazolyl)benzeneamine
Introduction：Basic information about CAS 92-36-4|4-(6-Methyl-2-benzothiazolyl)benzeneamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Dehydrothio-p-toluidine (DHPT) is a chemical intermediate used in dyestuff production. Dehydrothio-p-toluidine shows inhalation toxicity in acute and subchronic conditions[1].
Related Catalog
Research Areas >>OthersSignaling Pathways >>Others >>Others
In Vivo
Dehydrothio-p-toluidine (4 h) induces salivation, pawing and chewing motions, lachrymation, sporadic fasciculations, rapid respiration and slight weight loss of mice under an average of 0.64 mg DHPT/L condition[1]. Dehydrothio-p-toluidine (4 h) induces sporadic nasal discharge and lethargy of mice under an average of 2.41 mg DHPT/L condition[1]. Dehydrothio-p-toluidine (6 h/day on 5 days followed by two rest days and then by five additional days of exposures; 0.6 mg DHPT/L) decreases the erythrocyte count, haemoglobin level and relative number of lymphocytes than in the controls, excrets a larger volume of less-concentrated urine, produces liver changes characterized by hepatocyte hyper trophy and proliferation of bile-duct epithelial cells and induxes thymic necrosis and depletion of lymphocytes after the tenth exposure[1].
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 22,289,1984 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
68 gm/m3/6H/12D-I
TOXIC EFFECTS :
Liver - changes in liver weight Endocrine - changes in spleen weight Blood - changes in erythrocyte (RBC) count
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 22,289,1984
Safety Information
Symbol
GHS07
Signal Word
Warning
Hazard Statements
H315-H319-H335
Precautionary Statements
P261-P305 + P351 + P338
Personal Protective Equipment
dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes
Xi: Irritant;
Risk Phrases
R36/37/38
Safety Phrases
S26;S36
RIDADR
NONH for all modes of transport
RTECS
DL2820000
HS Code
2934999090
Customs
HS Code
2934999090
Summary
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles1
More Articles
Inhalation toxicity of dehydrothio-p-toluidine.
Food Chem. Toxicol. 22(4) , 289-92, (1984)
The acute inhalation toxicity of dehydrothio -p-toluidine ( DHPT ; CAS Registry No. 92-36-4) was determined by exposing groups of young adult Crl-CD rats for single 4-hr periods. Death resulted when t...
