CAS 39524-08-8|Asperosaponin VI

Introduction：Basic information about CAS 39524-08-8|Asperosaponin VI, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Asperosaponin VI BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Asperosaponin VI
CAS Number	39524-08-8	Molecular Weight	929.096
Density	1.43	Boiling Point	990.2±65.0 °C at 760 mmHg
Molecular Formula	C₄₇H₇₆O₁₈	Melting Point	/
MSDS	/	Flash Point	282.1±27.8 °C

Names

Name	Akebia saponin D
Synonym	More Synonyms

Asperosaponin VI BiologicalActivity

Description	Asperosaponin VI, A saponin component from Dipsacus asper wall, induces osteoblast differentiation through BMP‐2/p38 and ERK1/2 pathway[1]. Asperosaponin Ⅵ inhibits apoptosis in hypoxia-induced cardiomyocyte by increasing the Bcl-2/Bax ratio and decreasing active caspase-3 expression, as well as enhancing of p-Akt and p-CREB[2].
Related Catalog	Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cardiovascular Disease
References	[1]. Niu Y, et al. Asperosaponin VI, a saponin component from Dipsacus asper wall, induces osteoblast differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway. Phytother Res. 2011 Nov;25(11):1700-6. [2]. Li C, et al. Asperosaponin VI protects cardiac myocytes from hypoxia-induced apoptosis via activation of the PI3K/Akt and CREB pathways. Eur J Pharmacol. 2010 Dec 15;649(1-3):100-7.

Description

Asperosaponin VI, A saponin component from Dipsacus asper wall, induces osteoblast differentiation through BMP‐2/p38 and ERK1/2 pathway[1]. Asperosaponin Ⅵ inhibits apoptosis in hypoxia-induced cardiomyocyte by increasing the Bcl-2/Bax ratio and decreasing active caspase-3 expression, as well as enhancing of p-Akt and p-CREB[2].

Related Catalog

Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cardiovascular Disease

References

[1]. Niu Y, et al. Asperosaponin VI, a saponin component from Dipsacus asper wall, induces osteoblast differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway. Phytother Res. 2011 Nov;25(11):1700-6.

[2]. Li C, et al. Asperosaponin VI protects cardiac myocytes from hypoxia-induced apoptosis via activation of the PI3K/Akt and CREB pathways. Eur J Pharmacol. 2010 Dec 15;649(1-3):100-7.

Chemical & Physical Properties

Density	1.43
Boiling Point	990.2±65.0 °C at 760 mmHg
Molecular Formula	C₄₇H₇₆O₁₈
Molecular Weight	929.096
Flash Point	282.1±27.8 °C
Exact Mass	928.503174
PSA	294.98000
LogP	4.18
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.627
InChIKey	CCRXMHCQWYVXTE-JCWTXCFUSA-N
SMILES	CC1(C)CCC2(C(=O)OC3OC(COC4OC(CO)C(O)C(O)C4O)C(O)C(O)C3O)CCC3(C)C(=CCC4C5(C)CCC(OC6OCC(O)C(O)C6O)C(C)(CO)C5CCC43C)C2C1

Safety Information

Hazard Codes	Xi
Safety Phrases	24/25
HS Code	29389090

Synonyms

3-O-(triphenylmethyl)prop-1-yn-3-ol

Asperosaponin

D-Glucopyranose, 1-O-[(5ξ,8ξ,9ξ,10ξ,17ξ,18ξ)-3-(α-L-arabinopyranosyloxy)-23-hydroxy-28-oxoolean-12-en-28-yl]-6-O-D-glucopyranosyl-

1-O-[(5ξ,8ξ,9ξ,10ξ,17ξ,18ξ)-3-(α-L-Arabinopyranosyloxy)-23-hydroxy-28-oxoolean-12-en-28-yl]-6-O-D-glucopyranosyl-D-glucopyranose

Asperosaponin VI

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