CAS 39515-41-8|fenpropathrin [ANSI]
Introduction：Basic information about CAS 39515-41-8|fenpropathrin [ANSI], including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | fenpropathrin [ANSI] | ||
|---|---|---|---|
| CAS Number | 39515-41-8 | Molecular Weight | 349.423 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 448.2±35.0 °C at 760 mmHg |
| Molecular Formula | C22H23NO3 | Melting Point | 50 - 51ºC |
| MSDS | ChineseUSA | Flash Point | 195.5±16.2 °C |
| Symbol | GHS06, GHS09 | Signal Word | Danger |
Names
| Name | fenpropathrin |
|---|---|
| Synonym | More Synonyms |
fenpropathrin [ANSI] BiologicalActivity
| Description | Fenpropathrin is a synthetic pyrethroid insecticide in agriculture. Fenpropathrin may induces parkinsonian symptoms progressively[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
| References | [1]. Jing Xiong, et al. Fenpropathrin, a Widely Used Pesticide, Causes Dopaminergic Degeneration. Mol Neurobiol. 2016 Mar;53(2):995-1008. |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 448.2±35.0 °C at 760 mmHg |
| Melting Point | 50 - 51ºC |
| Molecular Formula | C22H23NO3 |
| Molecular Weight | 349.423 |
| Flash Point | 195.5±16.2 °C |
| Exact Mass | 349.167786 |
| PSA | 59.32000 |
| LogP | 5.48 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.552 |
| InChIKey | XQUXKZZNEFRCAW-UHFFFAOYSA-N |
| SMILES | CC1(C)C(C(=O)OC(C#N)c2cccc(Oc3ccccc3)c2)C1(C)C |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 18 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 870 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2500 ug/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - rigidity (including catalepsy) Behavioral - aggression
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 58 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 740 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 210 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 510 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Bird - chicken
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - duck
- DOSE/DURATION :
- 1089 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TYPE OF TEST :
- Micronucleus test
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 10 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 341,169,1995
- TYPE OF TEST :
- Micronucleus test
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 10 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 341,169,1995
Safety Information
| Symbol | GHS06, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H312-H330-H410 |
| Precautionary Statements | P260-P273-P280-P284-P301 + P310-P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | T+,N |
| Risk Phrases | 21-25-26-50/53 |
| Safety Phrases | S28-S36/37-S38-S45-S60-S61 |
| RIDADR | UN 2811 6.1/PG 2 |
| RTECS | GZ2090000 |
| HS Code | 2926909010 |
Customs
| HS Code | 2926909010 |
|---|
Articles31
More Articles| The molecular marker of kdr against fenpropathrin in Tetranychus cinnabarinus. J. Econ. Entomol. 106(6) , 2457-66, (2013) The carmine spider mite, Tetranychus cinnabarinus (Boisduval), is one of the most important pests in agricultural industry. Pyrethroid insecticide has been used to control insects and mites worldwide.... | |
| Spirodela polyrhiza stimulates the growth of its endophytes but differentially increases their fenpropathrin-degradation capabilities. Chemosphere 125 , 33-40, (2015) In situ remediation of organic contaminants via physical, chemical, and biological approaches is a practical technique for cleansing contaminated water and soil. In the present study, we showed that t... | |
| Combining ligand-based pharmacophore modeling, quantitative structure-activity relationship analysis and in silico screening for the discovery of new potent hormone sensitive lipase inhibitors. J. Med. Chem. 51 , 6478-94, (2008) Hormone sensitive lipase (HSL) has been recently implicated in diabetes and obesity, prompting attempts to discover new HSL inhibitors. Toward this end, we explored the pharmacophoric space of HSL inh... |
Synonyms
| TAME |
| PLATINO |
| rac-(R)-cyano(3-phenoxyphenyl)methyl 2,2,3,3-tetramethylcyclopropane-1-carboxylate |
| (RS)-α-cyano-3-phenoxybenzyl 2,2,3,3-tetramethylcyclopropanecarboxylate |
| Cyano(3-phenoxyphenyl)methyl 2,2,3,3-tetramethylcyclopropanecarboxylate |
| 2,2,3,3-Tetramethylcyclopropanecarboxylic acid cyano(3-phenoxyphenyl)methyl ester |
| Cyano(3-phenoxyphenyl)methyl 2,2,3,3-tetramethylcyclopropanecarboxylate (9CI) |
| α-Cyano-3-phenoxybenzyl 2,2,3,3-tetramethyl-1-cyclopropanecarboxylate |
| danimen |
| Fenpropathrin |
| Fenpropathrin PESTANAL(R),analytical standard |
| HERALD |
| Cyclopropanecarboxylic acid, 2,2,3,3-tetramethyl-, cyano(3-phenoxyphenyl)methyl ester |
| S 3206 |
| XE-938 |
| MFCD00144305 |
| RODY |
| a-Cyano-3-phenoxybenzyl 2,2,3,3-Tetramethylcyclopropanecarboxylate |
| fenpropanate |
| DANITOL |
| fenpropathrin [ANSI] |
| EINECS 254-485-0 |
| DIGITAL |
| AMITOL |
