Introduction：Basic information about CAS 2508-79-4|Methyldopate hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Methyldopate hydrochloride |
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| CAS Number | 2508-79-4 | Molecular Weight | 275.72900 |
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| Density | 1.243g/cm3 | Boiling Point | 398ºC at 760 mmHg |
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| Molecular Formula | C12H18ClNO4 | Melting Point | / |
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| MSDS | / | Flash Point | 194.5ºC |
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Names
| Name | ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoate,hydrochloride |
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| Synonym | More Synonyms |
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Methyldopate hydrochloride BiologicalActivity
| Description | Methyldopate hydrochloride is an ethyl ester hydrochloride prodrug of α-Methyldopa (α-MD; HY-B0225). Methyldopa (L-(-)-α-Methyldopa) is an α-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopate hydrochloride has the potential for severe hypertension research[1]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>GPCR/G Protein >>Adrenergic Receptor |
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| References | [1]. P D Walson, et al. Metabolic disposition and cardiovascular effects of methyldopate in unanesthetized rhesus monkeys. J Pharmacol Exp Ther. 1975 Oct;195(1):151-8. |
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Chemical & Physical Properties
| Density | 1.243g/cm3 |
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| Boiling Point | 398ºC at 760 mmHg |
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| Molecular Formula | C12H18ClNO4 |
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| Molecular Weight | 275.72900 |
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| Flash Point | 194.5ºC |
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| Exact Mass | 275.09200 |
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| PSA | 92.78000 |
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| LogP | 2.42310 |
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| Vapour Pressure | 6.62E-07mmHg at 25°C |
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| Index of Refraction | 1.572 |
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| InChIKey | QSRVZCCJDKYRRF-YDALLXLXSA-N |
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| SMILES | CCOC(=O)C(C)(N)Cc1ccc(O)c(O)c1.Cl |
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Synonyms
| METHYLDOPATE HYDROCHLORIDE |
| Methyldopa ethyl hydrochloride |
| EINECS 219-720-3 |
| Methyldopa ethyl ester hydrochloride |
| UNII-7PX435DN5A |
