Introduction：Basic information about CAS 78351-75-4|MY-5445, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | MY-5445 |
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| CAS Number | 78351-75-4 | Molecular Weight | 331.80 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 539.7±50.0 °C at 760 mmHg |
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| Molecular Formula | C20H14ClN3 | Melting Point | / |
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| MSDS | / | Flash Point | 280.2±30.1 °C |
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Names
| Name | N-(3-chlorophenyl)-4-phenylphthalazin-1-amine |
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| Synonym | More Synonyms |
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MY-5445 BiologicalActivity
| Description | MY-5445 is a specific phosphodiesterase type 5 (PDE5) inhibitor[1]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Metabolic Enzyme/Protease >>Phosphodiesterase (PDE) |
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| Target | PDE5 |
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| References | [1]. Nagendran J, et al. Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility. Circulation. 2007 Jul 17;116(3):238-48. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 539.7±50.0 °C at 760 mmHg |
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| Molecular Formula | C20H14ClN3 |
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| Molecular Weight | 331.80 |
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| Flash Point | 280.2±30.1 °C |
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| Exact Mass | 331.087616 |
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| PSA | 37.81000 |
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| LogP | 5.42 |
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| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
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| Index of Refraction | 1.712 |
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| InChIKey | CEHQLKSLMFIHBF-UHFFFAOYSA-N |
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| SMILES | Clc1cccc(Nc2nnc(-c3ccccc3)c3ccccc23)c1 |
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Safety Information
| Hazard Codes | Xi |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S26;S36 |
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Synonyms
| MY-5445 |
| N-(3-Chlorophenyl)-4-phenyl-1-phthalazinamine |
| Tocris-0432 |
| N-(3-chlorophenyl)-4-phenylphthalazin-1-amine |
| 1-Phthalazinamine, N-(3-chlorophenyl)-4-phenyl- |
