CAS 16642-92-5|trans-4-(Trifluoromethyl)cinnamic acid

Introduction：Basic information about CAS 16642-92-5|trans-4-(Trifluoromethyl)cinnamic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Safety Information
4. Customs
5. Articles1
6. Synonyms

Common Name	trans-4-(Trifluoromethyl)cinnamic acid
CAS Number	16642-92-5	Molecular Weight	216.157
Density	1.4±0.1 g/cm3	Boiling Point	279.2±35.0 °C at 760 mmHg
Molecular Formula	C₁₀H₇F₃O₂	Melting Point	231-233 °C(lit.)
MSDS	ChineseUSA	Flash Point	122.6±25.9 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	4-(Trifluoromethyl)cinnamic acid
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	279.2±35.0 °C at 760 mmHg
Melting Point	231-233 °C(lit.)
Molecular Formula	C₁₀H₇F₃O₂
Molecular Weight	216.157
Flash Point	122.6±25.9 °C
Exact Mass	216.039810
PSA	37.30000
LogP	3.37
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.526
InChIKey	ANRMAUMHJREENI-ZZXKWVIFSA-N
SMILES	O=C(O)C=Cc1ccc(C(F)(F)F)cc1

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2916399090

Customs

HS Code	2916399090
Summary	2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles1

Investigation of the influence of CYP1A2 and CYP2C19 genetic polymorphism on 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide (A77 1726) pharmacokinetics in leflunomide-treated patients with rheumatoid arthritis.

Drug Metab. Dispos. 37(10) , 2061-8, (2009)

Leflunomide is a disease-modifying antirheumatic drug used for the treatment of rheumatoid arthritis (RA). Cytochromes P450, mainly CYP1A2 and CYP2C19, may be involved in the transformation of lefluno...

Synonyms

PTF-CNA

QV1U1R DXFFF &&trans or E Form

4-Trifluoromethylcinnamic

trans-4-(Trifluoromethyl)cinnamic Acid

2-Propenoic acid, 3-[4-(trifluoromethyl)phenyl]-, (2E)-

(2E)-3-[4-(Trifluoromethyl)phenyl]-2-propenoic acid

(2E)-3-[4-(trifluoromethyl)phenyl]acrylic acid

4-(Trifluoromethyl)cinnamic Acid

MFCD00002696

RARECHEM BK HW 0019

Recommended......