CAS 3943-97-3|Methyl p-coumarate

Introduction：Basic information about CAS 3943-97-3|Methyl p-coumarate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Methyl p-coumarate BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	Methyl p-coumarate
CAS Number	3943-97-3	Molecular Weight	178.185
Density	1.2±0.1 g/cm3	Boiling Point	306.6±17.0 °C at 760 mmHg
Molecular Formula	C₁₀H₁₀O₃	Melting Point	144-145ºC
MSDS	/	Flash Point	132.8±13.7 °C

Names

Name	Methyl 4-hydroxycinnamate
Synonym	More Synonyms

Methyl p-coumarate BiologicalActivity

Description	Methyl p-coumarate (Methyl 4-hydroxycinnamate), an esterified derivative of p-Coumaric acid (pCA), is isolated from the flower of Trixis michuacana var longifolia. Methyl p-coumarate could inhibit the melanin formation in B16 mouse melanoma cells. Methyl p-coumarate also has strong in vitro inhibitory effect on A. alternata and other pathogens[1][2].
Related Catalog	Research Areas >>CancerResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>Fungal
References	[1]. Kubo I, et, al. Methyl p-coumarate, a melanin formation inhibitor in B16 mouse melanoma cells. Bioorg Med Chem. 2004 Oct 15;12(20):5349-54. [2]. Yuan S, et, al. Defense Responses, Induced by p-Coumaric Acid and Methyl p-Coumarate, of Jujube ( Ziziphus jujuba Mill.) Fruit against Black Spot Rot Caused by Alternaria alternate. J Agric Food Chem. 2019 Mar 13;67(10):2801-2810.

Description

Methyl p-coumarate (Methyl 4-hydroxycinnamate), an esterified derivative of p-Coumaric acid (pCA), is isolated from the flower of Trixis michuacana var longifolia. Methyl p-coumarate could inhibit the melanin formation in B16 mouse melanoma cells. Methyl p-coumarate also has strong in vitro inhibitory effect on A. alternata and other pathogens[1][2].

Related Catalog

Research Areas >>CancerResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>Fungal

References

[1]. Kubo I, et, al. Methyl p-coumarate, a melanin formation inhibitor in B16 mouse melanoma cells. Bioorg Med Chem. 2004 Oct 15;12(20):5349-54.

[2]. Yuan S, et, al. Defense Responses, Induced by p-Coumaric Acid and Methyl p-Coumarate, of Jujube ( Ziziphus jujuba Mill.) Fruit against Black Spot Rot Caused by Alternaria alternate. J Agric Food Chem. 2019 Mar 13;67(10):2801-2810.

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	306.6±17.0 °C at 760 mmHg
Melting Point	144-145ºC
Molecular Formula	C₁₀H₁₀O₃
Molecular Weight	178.185
Flash Point	132.8±13.7 °C
Exact Mass	178.062988
PSA	46.53000
LogP	1.64
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.593
InChIKey	NITWSHWHQAQBAW-DAXSKMNVSA-N
SMILES	COC(=O)C=Cc1ccc(O)cc1

Safety Information

Hazard Codes	Xi
HS Code	2918290000

Customs

HS Code	2918290000
Summary	HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

Synonyms

2-Propenoic acid, 3-(4-hydroxyphenyl)-, methyl ester

p-Hydroxycinnamic acid methyl ester

methyl (2E)-3-(4-hydroxyphenyl)prop-2-enoate

2-Propenoic acid, 3-(4-hydroxyphenyl)-, methyl ester, (2E)-

Cinnamic acid, p-hydroxy-, methyl ester

EINECS 223-531-1

Methyl 3-(4-hydroxyphenyl)acrylate

Methyl-4-hydroxy cinnamate

Methyl (2E)-3-(4-hydroxyphenyl)acrylate

Methyl 4-hydroxycinnamate

MFCD00157167

2-Propenoic acid, 3- (4-hydroxyphenyl)-, methyl ester

methyl trans-p-hydroxycinnamate

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