Introduction：Basic information about CAS 16481-54-2|Podophyllotoxin β-D-glucoside, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Podophyllotoxin β-D-glucoside |
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| CAS Number | 16481-54-2 | Molecular Weight | 576.546 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | 781.3±60.0 °C at 760 mmHg |
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| Molecular Formula | C28H32O13 | Melting Point | 152-154℃ |
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| MSDS | / | Flash Point | 258.2±26.4 °C |
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Names
| Name | Podophyllotoxin, 3-.β.-D-glucopyranoside |
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| Synonym | More Synonyms |
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Podophyllotoxin β-D-glucoside BiologicalActivity
| Description | Podophyllotoxin glucoside is a podophyllotoxin derivative, has anti-tumor effects[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| References | [1]. K R Hande, et al. Etoposide: four decades of development of a topoisomerase II inhibitor. Eur J Cancer |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Boiling Point | 781.3±60.0 °C at 760 mmHg |
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| Melting Point | 152-154℃ |
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| Molecular Formula | C28H32O13 |
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| Molecular Weight | 576.546 |
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| Flash Point | 258.2±26.4 °C |
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| Exact Mass | 576.184265 |
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| PSA | 171.83000 |
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| LogP | -0.66 |
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| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
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| Index of Refraction | 1.660 |
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| InChIKey | NXVJTGLCCSFGAT-QNDDJFOYSA-N |
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| SMILES | COc1cc(C2c3cc4c(cc3C(OC3OC(CO)C(O)C(O)C3O)C3COC(=O)C23)OCO4)cc(OC)c1OC |
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| Storage condition | 2-8C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- TP9002050
- CHEMICAL NAME :
- Podophyllotoxin, 4,6-O-benzylidene-beta-D-glucopyranoside
- CAS REGISTRY NUMBER :
- 16481-54-2
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C28-H32-O13
- MOLECULAR WEIGHT :
- 576.60
- WISWESSER LINE NOTATION :
- T E5 C665 FVO NO PO OHTT&&J DR CO1 DO1 EO1& JO- HT66 BO DO GOTJ CR& IQ JQ
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 340 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - mouse Cells - not otherwise specified
- DOSE/DURATION :
- 30 mg/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 37,2998,1977
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Synonyms
| Podophyllotoxin-7-O-glucoside |
| Podophyllotoxin 4-O-glucoside |
| (5R,5aR,8aR,9R)-8-Oxo-9-(3,4,5-trimethoxyphenyl)-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl β-D-glucopyranoside |
| Podophyllotoxin glucoside |
| Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-(β-D-glucopyranosyloxy)-5,8,8a,9-tetrahydro-5-(3,4,5-trimethoxyphenyl)-, (5R,5aR,8aR,9R)- |
| Podophyllotoxin, 3-β-D-glucopyranoside |
| Podophyllotoxin-4-O-glucoside |
| Podophyllotoxin-β-D-glucoside |
