Introduction：Basic information about CAS 13312-52-2|9-cis-β-Carotene, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 9-cis-β-Carotene |
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| CAS Number | 13312-52-2 | Molecular Weight | 536.873 |
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| Density | 0.9±0.1 g/cm3 | Boiling Point | 654.7±22.0 °C at 760 mmHg |
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| Molecular Formula | C40H56 | Melting Point | / |
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| MSDS | / | Flash Point | 346.0±17.2 °C |
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Names
| Name | 1,3,3-trimethyl-2-[(1E,3Z,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohexene |
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| Synonym | More Synonyms |
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9-cis-β-Carotene BiologicalActivity
| Description | 9-cis-β-Carotene, a precursor of retinal, is cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal. 9-cis-β-Carotene inhibits photoreceptor degeneration and restores retinal function in vivo. 9-cis-β-Carotene has the potential for the study of congenital stationary night blindness and fundus albipunctatus[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| In Vitro | 9-cis-β-Carotene (1 μM; 18 hours) formulates with the Miglyol 810 and the“antioxidant mix” is incubated to eye cups. The eye cups are isolated from the neuro-retina attached to the underlying RPE tissue from RPE65rd12 mouse. It prevents S- and M-cones degeneration and leads to over 2- and 9- fold higher m-opsin and s-opsin positive staining compares to the control group[1]. |
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| In Vivo | In a mouse model of retinoid cycle defect, RPE65rd12. Mice with an extract of Dunaliella Bardawil algae rich in 9-cis-β-Carotene (9CBC) rescues retinal function and preserves cone structure by oral administration[1]. |
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| References | [1]. Sher I, et al.Synthetic 9-cis-beta-carotene inhibits photoreceptor degeneration in cultures of eye cups from rpe65rd12 mouse model of retinoid cycle defect.Sci Rep. 2018 Apr 17;8(1):6130. |
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Chemical & Physical Properties
| Density | 0.9±0.1 g/cm3 |
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| Boiling Point | 654.7±22.0 °C at 760 mmHg |
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| Molecular Formula | C40H56 |
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| Molecular Weight | 536.873 |
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| Flash Point | 346.0±17.2 °C |
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| Exact Mass | 536.438232 |
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| LogP | 15.51 |
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| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
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| Index of Refraction | 1.566 |
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| InChIKey | OENHQHLEOONYIE-BVZAMQQESA-N |
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| SMILES | CC(C=CC=C(C)C=CC1=C(C)CCCC1(C)C)=CC=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C |
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Synonyms
| neo U-|A-Carotene |
| β,β-Carotene, (9cis)- |
| 9-cis-|A,|A-Carotene |
| 9-CIS-BETA-CAROTENE |
| (9cis)-β,β-Carotene |
| Neo-|A-carotene U |
| 9-cis-|A-Carotene |
