CAS 31218-83-4|Tsar
Introduction：Basic information about CAS 31218-83-4|Tsar, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Tsar | ||
|---|---|---|---|
| CAS Number | 31218-83-4 | Molecular Weight | 281.31 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 321.1±44.0 °C at 760 mmHg |
| Molecular Formula | C10H20NO4PS | Melting Point | <25℃ |
| MSDS | ChineseUSA | Flash Point | 148.0±28.4 °C |
| Symbol | GHS06, GHS09 | Signal Word | Danger |
Names
| Name | propetamphos |
|---|---|
| Synonym | More Synonyms |
Tsar BiologicalActivity
| Description | Propetamphos is an organophosphorus insecticide. Propetamphos causes cytotoxicity and oxidative stress[1][2]. |
|---|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Others >>Others |
| In Vivo | Propolis (100 mg/kg/天；口服；28 天) 对由 Propetamphos 诱导的 Wistar Albino 大鼠表现出抗自由基和抗氧化作用[1]。 |
| References | [1]. Kanbur M, et al. Antioxidant effect of propolis against exposure to propetamphos in rats. Ecotoxicol Environ Saf. 2009 Mar;72(3):909-15. [2]. Cetin E, et al. Propetamphos-induced changes in haematological and biochemical parameters of female rats: protective role of propolis. Food Chem Toxicol. 2010 Jul;48(7):1806-10. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 321.1±44.0 °C at 760 mmHg |
| Melting Point | <25℃ |
| Molecular Formula | C10H20NO4PS |
| Molecular Weight | 281.31 |
| Flash Point | 148.0±28.4 °C |
| Exact Mass | 281.085052 |
| PSA | 98.69000 |
| LogP | 1.61 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.495 |
| InChIKey | BZNDWPRGXNILMS-VQHVLOKHSA-N |
| SMILES | CCNP(=S)(OC)OC(C)=CC(=O)OC(C)C |
| Storage condition | APPROX 4°C |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 62400 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 37,1621,1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 564 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 35,1315,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 49 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953- Volume(issue)/page/year: 34,79,1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 130 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PSTDAN Pesticides. (Colour Pub. Pvt. Ltd., 126-A Dhuruwadi, Off Dr. Nariman Rd., Bombay 400-025, India) V.1- 1967- Volume(issue)/page/year: 15(10),37,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PSTDAN Pesticides. (Colour Pub. Pvt. Ltd., 126-A Dhuruwadi, Off Dr. Nariman Rd., Bombay 400-025, India) V.1- 1967- Volume(issue)/page/year: 15(10),37,1981 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2243 No. of Facilities: 6 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 6 (estimated)
Safety Information
| Symbol | GHS06, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 + H311-H330-H410 |
| Precautionary Statements | P260-P273-P280-P284-P301 + P310 + P330-P304 + P340 + P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | T: Toxic;N: Dangerous for the environment; |
| Risk Phrases | R25 |
| Safety Phrases | S37;S45;S60;S61 |
| RIDADR | UN 3018 |
| RTECS | GQ4750000 |
| Packaging Group | II |
| Hazard Class | 6.1(b) |
| HS Code | 2931900090 |
Customs
| HS Code | 2931900090 |
|---|---|
| Summary | 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0% |
Articles25
More Articles| Activated transformations of organophosphorus insecticides in the case of non-AChE inhibitory oxons. Pest Manag. Sci. 58(11) , 1107-17, (2002) Many organophosphorus (OP) compounds are of the thiono form and in insects or animals are converted by microsomal mixed function oxidases (MFO) into the oxon forms which inhibit acetylcholinesterase (... | |
| Insecticide susceptibility of cat flea (Siphonaptera: Pulicidae) pupae. J. Econ. Entomol. 89(2) , 421-7, (1996) Studies were conducted to investigate what protective nature the cocoon and nylon carpeting has against the performance of insecticides directed at cat flea, Ctenocephalides felis (Bouché), pupae deve... | |
| Survey of levels of propetamphos and diazinon used to control sheep scab in Northern Ireland. Vet. Rec. 126(11) , 263-5, (1990) As a result of an increase in the incidence of sheep scab in Northern Ireland, the concentrations of propetamphos and diazinon were measured during 1987 and 1988 in fleece and liquid dip samples from ... |
Synonyms
| 1-methylethyl (2E)-3-[[(ethylamino)methoxyphosphinothioyl]oxy]-2-butenoate |
| Propetamphos [BAN] |
| PROPETAMPHOS |
| Safrotin S 200 |
| Deadmag |
| (E)-3-Hydroxycrotonic Acid Isopropyl Ester O-Ester with o-Methyl Ethylphosphoramidothioate |
| 2-Butenoic acid, 3-[[(ethylamino)methoxyphosphinothioyl]oxy]-, 1-methylethyl ester, (2E)- |
| Seraphos |
| propan-2-yl (2E)-3-{[(ethylamino)(methoxy)phosphorothioyl]oxy}but-2-enoate |
| Isopropyl-(2E)-3-{[(ethylamino)(methoxy)phosphorothioyl]oxy}but-2-enoat |
| propan-2-yl (E)-3-[ethylamino(methoxy)phosphinothioyl]oxybut-2-enoate |
| EINECS 250-517-2 |
| 1-methylethyl (2E)-3-{[(ethylamino)(methoxy)phosphorothioyl]oxy}but-2-enoate |
| Isopropyl 3-(ethylamino(methoxy)phosphinothioyloxy)isocrotonate |
| PS1076_SUPELCO |
| propan-2-yl (2E)-3-{[(Ξ)-N-ethyl-P-methoxyphosphoramidothioyl]oxy}but-2-enoate |
| Blotic |
| (E)-1-Methylethyl 3-[[(Ethylamino)methoxyphosphinothioyl]oxy]-2-butenoate |
| (E)-O-2-Isopropoxycarbonyl-1-methylvinyl O-Methyl Ethylphosphoramidothioate |
| MFCD00137384 |
| Isopropyl (2E)-3-{[(ethylamino)(methoxy)phosphorothioyl]oxy}but-2-enoate |
| Tsar |
| 2-Butenoic acid, 3-(((ethylamino)methoxyphosphinothioyl)oxy)-, 1-methylethyl ester, (E)- |
| Isopropyl (2E)-3-{[(ethylamino)(methoxy)phosphorothioyl]oxy}-2-butenoate |
| SAN 322I |
| (RS)-[(E)-O-2-isopropoxycarbonyl-1-methylvinyl O-methyl ethylphosphoramidothioate] |
