CAS 41060-16-6|Panicolin

Introduction：Basic information about CAS 41060-16-6|Panicolin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Panicolin BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	Panicolin
CAS Number	41060-16-6	Molecular Weight	314.29
Density	1.4±0.1 g/cm3	Boiling Point	573.6±50.0 °C at 760 mmHg
Molecular Formula	C₁₇H₁₄O₆	Melting Point	254-256℃
MSDS	/	Flash Point	215.5±23.6 °C

Names

Name	Skullcapflavone I
Synonym	More Synonyms

Panicolin BiologicalActivity

Description	Skullcapflavone I can be isolated from A. nallamalayana. Skullcapflavone I inhibits collagenase and elastase enzyme with IC50s of 106.74 μM and 186.70 μM. Skullcapflavone I has anticancer activities by down-regulating miR-23a[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Epigenetics >>MicroRNASignaling Pathways >>Metabolic Enzyme/Protease >>Elastase
References	[1]. Yang B, et al. Anti-cancer, Anti-collagenase and Anti-elastase Potentials of Some Natural Derivatives: In vitro and in silico Studies. J Oleo Sci. 2023;72(5):557-570. [2]. Cui J, et al. Skullcapflavone I has a potent anti-pancreatic cancer activity by targeting miR-23a. Biofactors. 2020 Sep;46(5):821-830.

Description

Skullcapflavone I can be isolated from A. nallamalayana. Skullcapflavone I inhibits collagenase and elastase enzyme with IC50s of 106.74 μM and 186.70 μM. Skullcapflavone I has anticancer activities by down-regulating miR-23a[1].

Related Catalog

Research Areas >>CancerSignaling Pathways >>Epigenetics >>MicroRNASignaling Pathways >>Metabolic Enzyme/Protease >>Elastase

References

[1]. Yang B, et al. Anti-cancer, Anti-collagenase and Anti-elastase Potentials of Some Natural Derivatives: In vitro and in silico Studies. J Oleo Sci. 2023;72(5):557-570.

[2]. Cui J, et al. Skullcapflavone I has a potent anti-pancreatic cancer activity by targeting miR-23a. Biofactors. 2020 Sep;46(5):821-830.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	573.6±50.0 °C at 760 mmHg
Melting Point	254-256℃
Molecular Formula	C₁₇H₁₄O₆
Molecular Weight	314.29
Flash Point	215.5±23.6 °C
Exact Mass	314.079041
PSA	89.13000
LogP	2.06
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.646
InChIKey	CZRGNFVQUYWGKP-UHFFFAOYSA-N
SMILES	COc1cc(O)c2c(=O)cc(-c3ccccc3O)oc2c1OC

Safety Information

Hazard Codes	T+
HS Code	2914509090

Customs

HS Code	2914509090
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Synonyms

SKULLCAPFLAVONE I

5-Hydroxy-2-(2-hydroxyphenyl)-7,8-dimethoxy-4H-chromen-4-one

4H-1-Benzopyran-4-one, 5-hydroxy-2-(2-hydroxyphenyl)-7,8-dimethoxy-

Panicolin

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