CAS 82209-76-5|Andrographoside

Introduction：Basic information about CAS 82209-76-5|Andrographoside, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Andrographoside BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles6
6. Synonyms

Common Name	Andrographoside
CAS Number	82209-76-5	Molecular Weight	512.590
Density	1.4±0.1 g/cm3	Boiling Point	747.2±60.0 °C at 760 mmHg
Molecular Formula	C₂₆H₄₀O₁₀	Melting Point	/
MSDS	USA	Flash Point	247.2±26.4 °C

Names

Name	Andrographoside
Synonym	More Synonyms

Andrographoside BiologicalActivity

Description	Andrographiside is a labdane diterpenoid glucoside that can be isolated from the leaves of Andrographis paniculata Nees. Andrographiside has antihepatotoxic and antioxidative effects. Andrographiside shows protective effects on mice with hepatotoxicity induced by carbon tetrachloride or tert-butylhydroperoxide (tBHP)[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Others >>Others
References	[1]. Kapil A, et al. Antihepatotoxic effects of major diterpenoid constituents of Andrographis paniculata. Biochem Pharmacol. 1993 Jul 6;46(1):182-5.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	747.2±60.0 °C at 760 mmHg
Molecular Formula	C₂₆H₄₀O₁₀
Molecular Weight	512.590
Flash Point	247.2±26.4 °C
Exact Mass	512.262146
PSA	166.14000
LogP	-0.41
Vapour Pressure	0.0±5.6 mmHg at 25°C
Index of Refraction	1.602
InChIKey	VUEPOIYXKZTLMD-ANZZXSATSA-N
SMILES	C=C1CCC2C(C)(COC3OC(CO)C(O)C(O)C3O)C(O)CCC2(C)C1CC=C1C(=O)OCC1O
Storage condition	?20°C

Safety Information

Hazard Codes	Xi
RIDADR	NONH for all modes of transport

Articles6

[Isolation and structure of two new diterpenoid glucosides from Andrographis paniculata Nees].

Yao Xue Xue Bao 17(6) , 435-40, (1982)

[Pharmacological studies on thirteen kinds of injections from Andrographis paniculata. I. Antipyretic, anti-inflammatory effects and toxicity].

Zhong Yao Tong Bao 10(7) , 38-42, (1985)

[Comprehensive evaluation of cuanhuning injection].

Zhongguo Zhong Yao Za Zhi 26(6) , 427-9, (2001)

Synonyms

[(1R,2R,4aS,5R,8aS)-2-Hydroxy-5-{(2E)-2-[(4S)-4-hydroxy-2-oxodihydro-3(2H)-furanylidene]ethyl}-1,4a-dimethyl-6-methylenedecahydro-1-naphthalenyl]methyl β-D-glucopyranoside

2(3H)-Furanone, 3-[2-[(1R,4aS,5R,6R,8aS)-5-[(β-D-glucopyranosyloxy)methyl]decahydro-6-hydroxy-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-, (3E,4S)-

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