CAS 18598-63-5|L-Cysteine methyl ester hydrochloride

Introduction：Basic information about CAS 18598-63-5|L-Cysteine methyl ester hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. L-Cysteine methyl ester hydrochloride BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Customs
7. Articles42
8. Synonyms

Common Name	L-Cysteine methyl ester hydrochloride
CAS Number	18598-63-5	Molecular Weight	171.646
Density	/	Boiling Point	197.2ºC at 760 mmHg
Molecular Formula	C₄H₁₀ClNO₂S	Melting Point	142 °C (dec.)(lit.)
MSDS	ChineseUSA	Flash Point	73.1ºC
Symbol	GHS07	Signal Word	Warning

Names

Name	methyl (2R)-2-amino-3-sulfanylpropanoate,hydrochloride
Synonym	More Synonyms

L-Cysteine methyl ester hydrochloride BiologicalActivity

Description	Mecysteine hydrochloride is an antitussive, and an expectorant agent, used to relieve breathing difficulties caused by mucus.
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology

Chemical & Physical Properties

Boiling Point	197.2ºC at 760 mmHg
Melting Point	142 °C (dec.)(lit.)
Molecular Formula	C₄H₁₀ClNO₂S
Molecular Weight	171.646
Flash Point	73.1ºC
Exact Mass	171.012070
PSA	91.12000
LogP	0.91880
Vapour Pressure	0.384mmHg at 25°C
Index of Refraction	-2.5 ° (C=20, MeOH)
InChIKey	WHOHXJZQBJXAKL-DFWYDOINSA-M
SMILES	COC(=O)C(N)CS.[Cl-]

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HA2460000

CHEMICAL NAME :: Cysteine, methyl ester, hydrochloride, L-

CAS REGISTRY NUMBER :: 18598-63-5

LAST UPDATED :: 199210

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C4-H9-N-O2-S.Cl-H

MOLECULAR WEIGHT :: 171.66

WISWESSER LINE NOTATION :: SH1YZVO1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 24,2331,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1340 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,829,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 60 gm/kg/30D-C

TOXIC EFFECTS :: Liver - other changes Kidney, Ureter, Bladder - other changes Blood - normocytic anemia

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 14,1407,1980

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	HA2460000
HS Code	2930909090

Customs

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles42

Steroidal sapogenins and glycosides from the fibrous roots of Ophiopogon japonicus and Liriope spicata var. prolifera with anti-inflammatory activity.

Chem. Pharm. Bull. 63(3) , 187-94, (2015)

Two new steroidal glycosides (1 and 2), together with 15 known compounds (3-17) were isolated from the fibrous roots of Ophiopogon japonicus, and three new steroidal glycosides (18-20), together with ...

Triterpene glycosides and other polar constituents of shea (Vitellaria paradoxa) kernels and their bioactivities.

Phytochemistry 108 , 157-70, (2014)

The MeOH extract of defatted shea (Vitellaria paradoxa; Sapotaceae) kernels was investigated for its constituents, and fifteen oleanane-type triterpene acids and glycosides, two steroid glucosides, tw...

The role of hydrogen bonding in the selectivity of L-cysteine methyl ester (CYSM) and L-cysteine ethyl ester (CYSE) for chloride ion.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 61(5) , 845-54, (2005)

The interaction of cysteamine (CY), L-cysteine methyl ester (CYSM), and L-cysteine ethyl ester (CYSE) with nitrate, sulfate, perchlorate, dihydrogen phosphate, and chloride ions was investigated using...

Synonyms

Actiol

H-Cys-OMe·HCl

Mecystein HCl

cysteine methyl ester hydrochloride

methyl L-cysteinate hydrochloride

Acdrile

MFCD00038985

Methyl L-cysteinate hydrochloride (1:1)

EINECS 242-435-0

L-Cysteine, methyl ester, hydrochloride (1:1)

hydrochloride*H-Cys-OMe

Methyl cysteine HCl

H-Cys-OMe.HCl

L-Cysteine Methyl Ester Hydrochloride

L-Cysteinemethylesterhydrochloride

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