CAS 445-29-4|2-Fluorobenzoic acid
Introduction：Basic information about CAS 445-29-4|2-Fluorobenzoic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Fluorobenzoic acid | ||
|---|---|---|---|
| CAS Number | 445-29-4 | Molecular Weight | 140.11 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 244.7±13.0 °C at 760 mmHg |
| Molecular Formula | C7H5FO2 | Melting Point | 122-125 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 101.8±19.8 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 2-fluorobenzoic acid |
|---|---|
| Synonym | More Synonyms |
2-Fluorobenzoic acid BiologicalActivity
| Description | 2-Fluorobenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
|---|---|
| Related Catalog | Research Areas >>Others |
| In Vitro | 2-氟苯甲酸可用于制备 zaragozic acid A 类似物。也用作有机化学合成中间体。 |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 244.7±13.0 °C at 760 mmHg |
| Melting Point | 122-125 °C(lit.) |
| Molecular Formula | C7H5FO2 |
| Molecular Weight | 140.11 |
| Flash Point | 101.8±19.8 °C |
| Exact Mass | 140.027359 |
| PSA | 37.30000 |
| LogP | 1.86 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.537 |
| InChIKey | NSTREUWFTAOOKS-UHFFFAOYSA-N |
| SMILES | O=C(O)c1ccccc1F |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 183,427,1936
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01726 *** REVIEWS *** TOXICOLOGY REVIEW IMSUAI Industrial Medicine and Surgery. (Northbrook, IL) V.18-42, 1949-73. For publisher information, see IOHSA5. Volume(issue)/page/year: 19,535,1950
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H335 |
| Precautionary Statements | P261 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S22-S26-S28-S24/25-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | DH0250000 |
| HS Code | 2916399090 |
Customs
| HS Code | 2916399090 |
|---|---|
| Summary | 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
Articles14
More Articles| Degradation of 2-bromo-, 2-chloro- and 2-fluorobenzoate by Pseudomonas putida CLB 250. FEMS Microbiol. Lett. 51(1) , 143-7, (1989) Pseudomonas putida strain CLB 250 (DSM 5232) utilized 2-bromo-, 2-chloro- and 2-fluorobenzoate as sole source of carbon and energy. Degradation is suggested to be initiated by a dioxygenase liberating... | |
| The preparation of zaragozic acid A analogues by directed biosynthesis. J. Antibiot. 47(11) , 1290-4, (1994) Zaragozic acid A analogues are produced by an unidentified sterile fungus when it is exogenously supplied with 2-thiophenecarboxylic acid, 3-thiophenecarboxylic acid, 2-furoic acid, 2-fluorobenzoic ac... | |
| Titration of nonstabilized diazoalkane solutions by fluorine NMR. J. Org. Chem. 77(2) , 1181-5, (2012) A new protocol for titrating nonstabilized diazoalkane solutions by quantitative (19)F NMR is reported. An excess of 2-fluorobenzoic acid dissolved in CDCl(3) is treated with the diazoalkane solution ... |
Synonyms
| Benzoic acid, 2-fluoro- |
| MFCD00002405 |
| EINECS 207-158-1 |
| o-Fluorobenzoic acid |
| 2-Fluorobenzoic acid |
| QVR BF |
