CAS 66839-66-5|(Lys3)-Bombesin
Introduction：Basic information about CAS 66839-66-5|(Lys3)-Bombesin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (Lys3)-Bombesin | ||
|---|---|---|---|
| CAS Number | 66839-66-5 | Molecular Weight | 1591.83 |
| Density | / | Boiling Point | / |
| Molecular Formula | C71H110N22O18S | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | / |
Names
| Name | [Lys3]-Bombesin,Pyr-QKLGNQWAVGHLM-NH2 |
|---|---|
| Synonym | More Synonyms |
(Lys3)-Bombesin BiologicalActivity
| Description | [Lys3]-Bombesin is a biological active peptide. (PET (Positron Emission Tomography) imaging of [Lys3]-bombesin is able to detect gastrin-releasing peptide receptor (GRPR) positive prostate cancer. An immunoconjugate of [Lys3]-bombesin and corresponding monoclonal antibody can specifically induce (CD64)-dependent monocyte and neutrophil-mediated lysis of small cell carcinoma.) |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
Chemical & Physical Properties
| Molecular Formula | C71H110N22O18S |
|---|---|
| Molecular Weight | 1591.83 |
| Exact Mass | 1590.81000 |
| PSA | 675.55000 |
| LogP | 2.97390 |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
Articles3
More Articles| Bombesin receptors in distinct tissue compartments of human pancreatic diseases. Lab. Invest. 80 , 1807-1817, (2000) Overexpression of receptors for regulatory peptides in various human diseases is reportedly of clinical interest. Among these peptides, bombesin and gastrin-releasing peptide (GRP) have been shown to ... | |
| Modulation of bombesin-induced phosphatidylinositol hydrolysis in a small-cell lung-cancer cell line. Biochem. J. 255 , 403-410, (1988) Bombesin is an amphibian tetradecapeptide whose mammalian homologue, gastrin-releasing peptide (GRP), is produced by many small-cell lung-cancer (SCLC) cells, and which can function in an autocrine gr... | |
| Investigation of molecular structure of bombesin and its modified analogues nonadsorbed and adsorbed on electrochemically roughened silver surface. Biopolymers 89 , 506-521, (2008) This work describes the molecular structure of bombesin (BN) and its analogs on the basis of the absorption infrared and Raman results described below. In these analogues is replaced one ([D-Phe12]BN,... |
Synonyms
| bombesin-3-L-lysine |
| PYROGLU-GLN-LYS-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET NH2 |
| PGLU-GLN-LYS-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2 |
| GLP-GLN-LYS-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2 |
| [LYS3]-BOMBESIN |
| PYR-QKLGNQWAVGHLM-NH2 |
| PYR-GLN-LYS-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2 |
