CAS 39024-57-2|(Leu15)-Gastrin I (human)
| Common Name | (Leu15)-Gastrin I (human) | ||
|---|---|---|---|
| CAS Number | 39024-57-2 | Molecular Weight | 2080.16000 |
| Density | / | Boiling Point | / |
| Molecular Formula | C98H126N20O31 | Melting Point | / |
| MSDS | USA | Flash Point | / |
Names
| Name | [Leu15]-Gastrin I human |
|---|---|
| Synonym | More Synonyms |
(Leu15)-Gastrin I (human) BiologicalActivity
| Description | [Leu15]-Gastrin I (human) is a peptide. Gastrin exerts its function through G-protein-coupled receptor called the cholecystokinin (CCK) or CCK-B receptor (CCK-BR)[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Kleomenis Barlos, et al. Veresterung von partiell geschützten peptid-fragmenten mit harzen. Einsatz von 2-chlortritylchlorid zur synthese von Leu15 -gastrin I[J]. Tetrahedron Letters, 1989. |
Chemical & Physical Properties
| Molecular Formula | C98H126N20O31 |
|---|---|
| Molecular Weight | 2080.16000 |
| Exact Mass | 2078.89000 |
| PSA | 804.61000 |
| LogP | 3.65640 |
| InChIKey | CMVMLPDUAGUTOC-FPBFVHJESA-N |
| SMILES | CC(C)CC(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)C(Cc1ccc(O)cc1)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C1CCCN1C(=O)CNC(=O)C1CCC(=O)N1)C(=O)NC(CC(=O)O)C(=O)NC(Cc1ccccc1)C(N)=O |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles7
More Articles| [Syntheses of human little gastrin-I and its leucine-15, norleucine-15 and methoxinine-15 analogs]. Hoppe. Seylers. Z. Physiol. Chem. 364 , 157, (1983) Human little gastrin-I is known to exhibit a high tendency to air-oxidation of its methionine-15 residue to the corresponding S-oxide derivative, with concomitant loss of biological activity. Since it... | |
| Cholecystokinin(CCK)-A and CCK-B/gastrin receptors in human tumors. Cancer Res. 57 , 1377, (1997) Cholecystokinin (CCK)-A and CCK-B/gastrin receptors were evaluated with in vitro receptor autoradiography in 406 human tumors of various origins using a sulfated 125I-labeled CCK decapeptide analogue ... | |
| Gastrin does not stimulate growth of the rat pancreas. Scand. J. Gastroenterol. 31 , 404-410, (1996) Gastrin is thought to stimulate growth of the pancreas via gastrin/cholecystokinin (CCK)-B-type receptors. The aim of the present study was to examine the trophic response of the pancreas to exogenous... |
Synonyms
| [Leu15]-Gastrin I (human) |
