CAS 139026-64-5|[Lys8, Lys9]-Neurotensin (8-13)

Introduction：Basic information about CAS 139026-64-5|[Lys8, Lys9]-Neurotensin (8-13), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. [Lys8, Lys9]-Neurotensin (8-13) BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	[Lys8, Lys9]-Neurotensin (8-13)
CAS Number	139026-64-5	Molecular Weight	760.96400
Density	1.203 g/cm3	Boiling Point	1109.7ºC at 760 mmHg
Molecular Formula	C₃₈H₆₄N₈O₈	Melting Point	/
MSDS	/	Flash Point	624.9ºC

Names

Name	[Lys8,9]-Neurotensin (8-13),KKPYIL
Synonym	More Synonyms

[Lys8, Lys9]-Neurotensin (8-13) BiologicalActivity

Description	[Lys8, Lys9]-Neurotensin (8-13) (JMV438), a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2, with Ki values of 0.33 nM and 0.95 nM for hNTS1 and hNTS2 receptors, respectively[1].
Related Catalog	Signaling Pathways >>GPCR/G Protein >>Neurotensin ReceptorResearch Areas >>Neurological Disease
References	[1]. Emilie Eiselt, et al. Neurotensin Analogues Containing Cyclic Surrogates of Tyrosine at Position 11 Improve NTS2 Selectivity Leading to Analgesia without Hypotension and Hypothermia. ACS Chem Neurosci. 2019 Nov 20;10(11):4535-4544.

Chemical & Physical Properties

Density	1.203 g/cm3
Boiling Point	1109.7ºC at 760 mmHg
Molecular Formula	C₃₈H₆₄N₈O₈
Molecular Weight	760.96400
Flash Point	624.9ºC
Exact Mass	760.48500
PSA	272.30000
LogP	4.22940
InChIKey	JDVIBJLNEIKOTF-VDXNIVNJSA-N
SMILES	CCC(C)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)C(N)CCCCN)C(=O)NC(CC(C)C)C(=O)O
Storage condition	-20°C

Synonyms

[lys8,9]-neurotensin (8-13)

lys-lys-pro-tyr-ile-leu

h-lys-lys-pro-tyr-ile-leu-oh

kkpyil

(lys8,lys9)-neurotensin (8-13)

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