CAS 64-85-7|Desoxycorticosterone

Introduction：Basic information about CAS 64-85-7|Desoxycorticosterone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Desoxycorticosterone BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
5. Safety Information
6. Customs
7. Articles178
8. Synonyms

Common Name	Desoxycorticosterone
CAS Number	64-85-7	Molecular Weight	330.46100
Density	1.15 g/cm3	Boiling Point	488ºC at 760 mmHg
Molecular Formula	C₂₁H₃₀O₃	Melting Point	138-144 °C
MSDS	ChineseUSA	Flash Point	263.1ºC
Symbol	GHS02, GHS06, GHS08	Signal Word	Danger

Names

Name	11-deoxycorticosterone
Synonym	More Synonyms

Desoxycorticosterone BiologicalActivity

Description	Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor.
Related Catalog	Natural Products >>OthersResearch Areas >>Others
Target	Human Endogenous Metabolite
References	[1]. KAGAWA CM, et al. Action of new steroids in blocking effects of aldosterone and desoxycorticosterone on salt. Science. 1957 Nov 15;126(3281):1015-6.

Chemical & Physical Properties

Density	1.15 g/cm3
Boiling Point	488ºC at 760 mmHg
Melting Point	138-144 °C
Molecular Formula	C₂₁H₃₀O₃
Molecular Weight	330.46100
Flash Point	263.1ºC
Exact Mass	330.21900
PSA	54.37000
LogP	3.69590
Index of Refraction	1.559
InChIKey	ZESRJSPZRDMNHY-YFWFAHHUSA-N
SMILES	CC12CCC(=O)C=C1CCC1C2CCC2(C)C(C(=O)CO)CCC12
Storage condition	2-8℃
Water Solubility	slightly soluble

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HG0350000

CHEMICAL NAME :: 11-Deoxycorticosterone

CAS REGISTRY NUMBER :: 64-85-7

LAST UPDATED :: 199703

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C21-H30-O3

MOLECULAR WEIGHT :: 330.51

WISWESSER LINE NOTATION :: L E5 B666 OV MUTJ A E FV1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 14500 ug/kg

SEX/DURATION :: female 7 day(s) pre-mating female 1-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - delayed effects

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

DOSE :: 8750 ug/kg

SEX/DURATION :: female 7 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - uterus, cervix, vagina

MUTATION DATA

TYPE OF TEST :: DNA adduct

TEST SYSTEM :: Human Liver

DOSE/DURATION :: 2 mmol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 370,49,1996

Safety Information

Symbol	GHS02, GHS06, GHS08
Signal Word	Danger
Hazard Statements	H225-H301 + H311 + H331-H370
Precautionary Statements	P210-P260-P280-P301 + P310-P311
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R40;R48
Safety Phrases	S22-S24/25
RIDADR	UN 2811 6.1/PG 2
WGK Germany	3
RTECS	HG0350000
HS Code	2942000000

Customs

HS Code	2942000000

Articles178

Incorporation of electrochemical advanced oxidation processes in a multistage treatment system for sanitary landfill leachate.

Water Res. 81 , 375-87, (2015)

The current study has proved the technical feasibility of including electrochemical advanced oxidation processes (EAOPs) in a multistage strategy for the remediation of a sanitary landfill leachate th...

Electrochemical incineration of the antibiotic ciprofloxacin in sulfate medium and synthetic urine matrix.

Water Res. 83 , 31-41, (2015)

The degradation of 100 mL of 0.245 mM of the antibiotic ciprofloxacin in 0.05 M Na2SO4 at pH 3.0 has been studied by electrochemical oxidation with electrogenerated H2O2 (EO-H2O2), electro-Fenton (EF)...

Selenium-containing chrysin and quercetin derivatives: attractive scaffolds for cancer therapy.

J. Med. Chem. 58 , 4250-65, (2015)

Selenium-containing chrysin (SeChry) and 3,7,3',4'-tetramethylquercetin (SePQue) derivatives were synthesized by a microwave-based methodology. In addition to their improvement in terms of DPPH scaven...

Synonyms

EINECS 200-596-4

Desoxycorticosterone

(8S,9S,10R,13S,14S,17S)-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

MFCD00003661

Recommended......