CAS 2528-16-7|Monobenzyl phthalate
Introduction：Basic information about CAS 2528-16-7|Monobenzyl phthalate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Monobenzyl phthalate | ||
|---|---|---|---|
| CAS Number | 2528-16-7 | Molecular Weight | 256.253 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 441.1±28.0 °C at 760 mmHg |
| Molecular Formula | C15H12O4 | Melting Point | 106 °C |
| MSDS | / | Flash Point | 167.8±17.5 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 2-phenylmethoxycarbonylbenzoic acid |
|---|---|
| Synonym | More Synonyms |
Monobenzyl phthalate BiologicalActivity
| Description | Monobenzyl phthalate (2-((Benzyloxy)carbonyl)benzoic acid) is the urinary metabolite exposuring to phthalates, such as, diethylhexyl phthalate (DEHP)[1]. |
|---|---|
| Related Catalog | Research Areas >>Metabolic Disease |
| References | [1]. Meiping Tian, et al. Positive Association of Low-Level Environmental Phthalate Exposure With Sperm Motility Was Mediated by DNA Methylation: A Pilot Study. Chemosphere. 2019 Apr;220:459-467. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 441.1±28.0 °C at 760 mmHg |
| Melting Point | 106 °C |
| Molecular Formula | C15H12O4 |
| Molecular Weight | 256.253 |
| Flash Point | 167.8±17.5 °C |
| Exact Mass | 256.073547 |
| PSA | 63.60000 |
| LogP | 2.90 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.609 |
| InChIKey | XIKIUQUXDNHBFR-UHFFFAOYSA-N |
| SMILES | O=C(O)c1ccccc1C(=O)OCc1ccccc1 |
| Storage condition | Refrigerator |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1125 mg/kg
- SEX/DURATION :
- female 7-9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - other effects Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 10,365,1996
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1500 mg/kg
- SEX/DURATION :
- female 10-12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- REFERENCE :
- REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 10,365,1996
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1500 mg/kg
- SEX/DURATION :
- female 13-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - other effects Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 10,365,1996
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1500 mg/kg
- SEX/DURATION :
- female 7-9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- REFERENCE :
- REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 10,365,1996
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Phrases | 36 |
| Safety Phrases | 26 |
| RIDADR | NONH for all modes of transport |
| RTECS | CZ4325000 |
| HS Code | 2918990090 |
Customs
| HS Code | 2918990090 |
|---|---|
| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Articles21
More Articles| Feasibility of ultra-high performance liquid and gas chromatography coupled to mass spectrometry for accurate determination of primary and secondary phthalate metabolites in urine samples. Anal. Chim. Acta 853 , 625-36, (2014) Phthalates (PAEs) are ubiquitous toxic chemical compounds. During the last few years, some phthalate metabolites (MPAEs) have been proposed as appropriate biomarkers in human urine samples to determin... | |
| Determination and separation of bisphenol A, phthalate metabolites and structural isomers of parabens in human urine with conventional high-pressure liquid chromatography combined with electrospray ionisation tandem mass spectrometry. Anal. Bioanal. Chem 407(9) , 2509-18, (2015) Phthalates, bisphenol A (BPA) and parabens (PBs), organic chemicals widely used in everyday products, are considered to be endocrine disruptors. We propose a liquid chromatography-tandem mass spectrom... | |
| Monitoring of PAEMs and beta-agonists in urine for a small group of experimental subjects and PAEs and beta-agonists in drinking water consumed by the same subjects. J. Hazard. Mater. 277 , 169-79, (2014) This 5-month study contains two parts: (1) to monitor the concentrations of 11 phthalate esters metabolites (PAEMs) and two beta-agonists in human urine samples collected from a small group of consent... |
Synonyms
| Phthalic Acid Monobenzyl Ester |
| 2-HO2CC6H4CO2Bn |
| o-benzyloxycarbonylbenzoic acid |
| Benzyl Hydrogen Phthalate |
| 2-(benzyloxycarbonyl)benzoic acid |
| MFCD00020279 |
| 1,2-Benzenedicarboxylic acid 1-(phenylmethyl) ester,Phthalic acid monobenzyl ester |
| mono-Benzyl phthalate |
| Phthalic acid,benzyl ester |
| 1,2-Benzenedicarboxylic acid, mono(phenylmethyl) ester |
| EINECS 219-771-1 |
| Monobenzyl phthalate (mBzP) |
| Mono-n-benzyl phthalate |
| carboxybenzoic acid benzyl ester |
| Monobenzyl Phthalate |
| 2-[(Benzyloxy)carbonyl]benzoic acid |
| 1,2-Benzenedicarboxylic acid,mono(phenylmethyl) ester |
