CAS 16589-24-5|Sympatol {Tartrate}

Introduction：Basic information about CAS 16589-24-5|Sympatol {Tartrate}, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Sympatol {Tartrate} BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Sympatol {Tartrate}
CAS Number	16589-24-5	Molecular Weight	317.292
Density	1.159 g/cm3	Boiling Point	823.3ºC at 760 mmHg
Molecular Formula	C₂₂H₃₂N₂O₁₀	Melting Point	184 °C
MSDS	/	Flash Point	451.7ºC

Names

Name	Synephrine Tartrate
Synonym	More Synonyms

Sympatol {Tartrate} BiologicalActivity

Description	Synephrine (Oxedrine) hemitartrate, an alkaloid, is an α-adrenergic and β-adrenergic agonist derived from the Citrus aurantium. Synephrine hemitartrate is a sympathomimetic compound and can be used for weight loss[1][2].
Related Catalog	Signaling Pathways >>GPCR/G Protein >>Adrenergic ReceptorResearch Areas >>Neurological Disease
In Vivo	Synephrine (1 mg/kg; oral gavage; for 8 days; PVL and BDL rats) significantly ameliorates the hyperdynamic state in both PVL and BDL rats. The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index are significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance are enhanced by treatment of Synephrine[2]. Animal Model: Portal vein ligation (PVL) or bile duct ligation (BDL) rats[2]. Dosage: 1 mg/kg per 12 hours Administration: Oral gavage; for 8 days Result: The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index were significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance were enhanced.
References	[1]. Thomas JE, et al. STEMI in a 24-year-old man after use of a synephrine-containing dietary supplement: a case report and review of the literature. Tex Heart Inst J. 2009;36(6):586-90. [2]. Huang YT, et al. Hemodynamic effects of synephrine treatment in portal hypertensive rats. Jpn J Pharmacol. 2001 Feb;85(2):183-8.

Chemical & Physical Properties

Density	1.159 g/cm3
Boiling Point	823.3ºC at 760 mmHg
Melting Point	184 °C
Molecular Formula	C₂₂H₃₂N₂O₁₀
Molecular Weight	317.292
Flash Point	451.7ºC
Exact Mass	317.111053
PSA	220.04000
Vapour Pressure	1.08E-28mmHg at 25°C
Index of Refraction	13 ° (C=5, H2O)
InChIKey	KZZBAIXGUQOHKI-CEAXSRTFSA-N
SMILES	CNCC(O)c1ccc(O)cc1.CNCC(O)c1ccc(O)cc1.O=C(O)C(O)C(O)C(=O)O

Safety Information

Risk Phrases	R36/37/38
Safety Phrases	S26-S36/37/39

Synonyms

Corvasymton {Tartrate}

Sympathol {Tartrate}

DL-4-HYDROXY-ALPHA-(METHYLAMINOMETHYL)BENZYL ALCOHOL D-TARTRATE

EINECS 240-647-8

(±)-1-(4-Hydroxyphenyl)-2-methylaminoethanol tartrate

4-[1-hydroxy-2-(methylamino)ethyl]phenol 2,3-dihydroxybutanedioate (1:1)

1-(4-Hydroxyphenyl)-2-(methylamino)ethanol tartrate

2,3-dihydroxybutanedioic acid,4-[1-hydroxy-2-(methylamino)ethyl]phenol

Simpadren {Tartrate}

Sympatol {Tartrate}

Synephrine tartrate

4-[1-Hydroxy-2-(methylamino)ethyl]phenol 2,3-dihydroxysuccinate (1:1)

MFCD00151120

Benzenemethanol, 4-hydroxy-α-[(methylamino)methyl]-, 2,3-dihydroxybutanedioate (1:1) (salt)

Recommended......