CAS 13466-78-9|carene
| Common Name | carene | ||
|---|---|---|---|
| CAS Number | 13466-78-9 | Molecular Weight | 136.234 |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 171.4±0.0 °C at 760 mmHg |
| Molecular Formula | C10H16 | Melting Point | 25°C |
| MSDS | ChineseUSA | Flash Point | 46.1±0.0 °C |
| Symbol | GHS02, GHS07, GHS08 | Signal Word | Danger |
Names
| Name | car-3-ene |
|---|---|
| Synonym | More Synonyms |
carene BiologicalActivity
| Description | 3-Carene is a bicyclic monoterpene in essential oils extracted from pine trees. 3-Carene inhibits nociceptive stimulus-induced inflammatory infiltrates and COX-2 overexpression, and with antinociceptive effect. 3-Carene stimulates the activity and expression of alkaline phosphatase that is an early phase marker of osteoblastic differentiation[1][2]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
| References | [1]. Huang XL, e tal. Anti-inflammatory and antinociceptive effects of active ingredients in the essential oils from Gynura procumbens, a traditional medicine and a new and popular food material.J Ethnopharmacol. 2019 Jul 15;239:111916. [2]. Jeong JG, et al. Low concentration of 3-carene stimulates the differentiation of mouse osteoblastic MC3T3-E1 subclone 4 cells. Phytother Res. 2008 Jan;22(1):18-22. |
Chemical & Physical Properties
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 171.4±0.0 °C at 760 mmHg |
| Melting Point | 25°C |
| Molecular Formula | C10H16 |
| Molecular Weight | 136.234 |
| Flash Point | 46.1±0.0 °C |
| Exact Mass | 136.125198 |
| LogP | 4.37 |
| Appearance of Characters | Liquid | Clear colorless to slightly yellow |
| Vapour Pressure | 1.9±0.1 mmHg at 25°C |
| Index of Refraction | 1.479 |
| Stability | Stable. Flammable. Incompatible with strong oxidizing agents. |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 11,1053,1973 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 11,1053,1973
Safety Information
| Symbol | GHS02, GHS07, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H226-H304-H315-H317 |
| Precautionary Statements | P280-P301 + P310-P331-P333 + P313-P370 + P378-P403 + P235 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi |
| Risk Phrases | R10;R38;R43;R52/53 |
| Safety Phrases | 16-26-36/37-60-61-62-37-24 |
| RIDADR | UN 2319 3/PG 3 |
| WGK Germany | 2 |
| RTECS | FH8400000 |
| Packaging Group | III |
| Hazard Class | 3.2 |
| HS Code | 2902199090 |
Customs
| HS Code | 2902199090 |
|---|---|
| Summary | 2902199090 other cyclanes, cyclenes and cyclotherpenes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0% |
Articles31
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| Mechanisms for the formation of organic acids in the gas-phase ozonolysis of 3-carene. Phys. Chem. Chem. Phys. 11(21) , 4184-97, (2009) This paper describes experimental studies aimed at elucidating mechanisms for the formation of low-volatility organic acids in the gas-phase ozonolysis of 3-carene. Experiments were carried out in a s... |
Synonyms
| (±)-D3-Carene |
| Bicyclo[4.1.0]hept-3-ene, 3,7,7-trimethyl- |
| 3-Carene,stabilized |
| 4,7,7-Trimethyl-3-norcarene |
| MFCD00001315 |
| 3-δ-Carene |
| 3,7,7-trimethyl-bicyclo[4.1.0]hept-3-ene |
| 3,7,7-Trimethylbicyclo[4.1.0]hept-3-ene |
| d3-carene |
| (±)-3-Carene |
| 3-carene |
| EINECS 236-719-3 |
| carene |
| δ3-Carene |
| Isodiprene |
