Introduction：Basic information about CAS 136056-02-5|L-Phenylalanine-3-13C, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | L-Phenylalanine-3-13C |
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| CAS Number | 136056-02-5 | Molecular Weight | 166.18200 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C813CH11NO2 | Melting Point | 270-275ºC (dec.)(lit.) |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | (2R)-2-amino-3-phenylpropanoic acid |
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| Synonym | More Synonyms |
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L-Phenylalanine-3-13C BiologicalActivity
| Description | L-Phenylalanine-3-13C ((S)-2-Amino-3-phenylpropionic acid-3-13C) is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4]. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>Calcium ChannelSignaling Pathways >>Neuronal Signaling >>iGluRResearch Areas >>Metabolic DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>iGluR |
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| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
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| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |
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Chemical & Physical Properties
| Melting Point | 270-275ºC (dec.)(lit.) |
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| Molecular Formula | C813CH11NO2 |
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| Molecular Weight | 166.18200 |
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| Exact Mass | 166.08200 |
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| PSA | 63.32000 |
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| LogP | 1.34130 |
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| InChIKey | COLNVLDHVKWLRT-JCNVXSMLSA-N |
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| SMILES | NC(Cc1ccccc1)C(=O)O |
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Safety Information
| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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Synonyms
| L-Phenylalanine-3-13C |
| MFCD00084040 |
| L-Phenylalanine-|A-13C |
