Introduction：Basic information about CAS 138786-67-1|Pantoprazole sodium, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Pantoprazole sodium |
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| CAS Number | 138786-67-1 | Molecular Weight | 405.35200 |
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| Density | / | Boiling Point | 586.9ºC at 760 mmHg |
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| Molecular Formula | C16H14F2N3NaO4S | Melting Point | 199-202ºC |
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| MSDS | ChineseUSA | Flash Point | 308.7ºC |
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Names
| Name | Pantoprazole sodium |
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| Synonym | More Synonyms |
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Pantoprazole sodium BiologicalActivity
| Description | Pantoprazole sodium salt(SKF96022; Protonix) is a proton pump inhibitor drug used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.IC50 value:Target: proton pump inhibitor |
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| Related Catalog | Signaling Pathways >>Autophagy >>AutophagySignaling Pathways >>Membrane Transporter/Ion Channel >>Proton PumpResearch Areas >>Others |
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| References | [1]. http://www.drugbank.ca/drugs/DB00213 |
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Chemical & Physical Properties
| Boiling Point | 586.9ºC at 760 mmHg |
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| Melting Point | 199-202ºC |
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| Molecular Formula | C16H14F2N3NaO4S |
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| Molecular Weight | 405.35200 |
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| Flash Point | 308.7ºC |
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| Exact Mass | 405.05700 |
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| PSA | 94.68000 |
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| LogP | 3.53580 |
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| InChIKey | CGJRLPRCWSHOFU-UHFFFAOYSA-N |
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| SMILES | COc1ccnc(CS(=O)c2nc3cc(OC(F)F)ccc3[n-]2)c1OC.O.[Na+] |
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| Storage condition | -20°C Freezer |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DD8264000
- CHEMICAL NAME :
- 1H-Benzimidazole, 5-(difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridinyl)me thyl)sulfinyl)-, sodium salt
- CAS REGISTRY NUMBER :
- 138786-67-1
- LAST UPDATED :
- 199503
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C16-H14-F2-N3-O4-S.Na
- MOLECULAR WEIGHT :
- 405.38
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 747 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 15,801,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 256 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 15,801,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 15,801,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 395 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 15,801,1990
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Safety Information
| Hazard Codes | Xn:Harmful |
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| Risk Phrases | R20/21/22-37/38-41-48 |
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| Safety Phrases | S22-26-36/37/39-45 |
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| HS Code | 2933990090 |
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Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| Pantoprazole |
| MFCD01658543 |
| sodium 5-(difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide |
| Sodium 6-(difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide |
| Pantoprazole sodium |
| 1H-Benzimidazole, 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1) |
| protium |
| Sodium 5-(difluoromethoxy)-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl}benzimidazol-1-ide |
| 1H-benzimidazole, 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-, sodium salt |
| Protonix |
| 5-(Difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridinyl)methyl) sulfinyl)-1H-benzimidazole sodium |
| 1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1) |
| Pantoprazole Sodium Salt |
| Pantoprazole (sodium) |
