CAS 495-31-8|Nodakenin

Introduction：Basic information about CAS 495-31-8|Nodakenin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Nodakenin BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Nodakenin
CAS Number	495-31-8	Molecular Weight	408.399
Density	1.5±0.1 g/cm3	Boiling Point	635.4±55.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₄O₉	Melting Point	melting at 216°
MSDS	/	Flash Point	225.4±25.0 °C

Names

Name	Nodakenin
Synonym	More Synonyms

Nodakenin BiologicalActivity

Description	Nodakenin is a major coumarin glucoside in the root of Peucedanum decursivum Maxim. Nodakenin inhibits acetylcholinesterase (AChE) activity with an IC50 of 84.7 μM[1][2].
Related Catalog	Research Areas >>Inflammation/ImmunologySignaling Pathways >>Neuronal Signaling >>AChE
References	[1]. Kim DH, et al. Nodakenin, a coumarin compound, ameliorates scopolamine-induced memory disruption in mice. Life Sci. 2007 May 1;80(21):1944-50. [2]. Xiong Y, et al. The effects of nodakenin on airway inflammation, hyper-responsiveness and remodeling in a murine model of allergic asthma. Immunopharmacol Immunotoxicol. 2014 Oct;36(5):341-8.

Description

Nodakenin is a major coumarin glucoside in the root of Peucedanum decursivum Maxim. Nodakenin inhibits acetylcholinesterase (AChE) activity with an IC50 of 84.7 μM[1][2].

Related Catalog

Research Areas >>Inflammation/ImmunologySignaling Pathways >>Neuronal Signaling >>AChE

References

[1]. Kim DH, et al. Nodakenin, a coumarin compound, ameliorates scopolamine-induced memory disruption in mice. Life Sci. 2007 May 1;80(21):1944-50.

[2]. Xiong Y, et al. The effects of nodakenin on airway inflammation, hyper-responsiveness and remodeling in a murine model of allergic asthma. Immunopharmacol Immunotoxicol. 2014 Oct;36(5):341-8.

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	635.4±55.0 °C at 760 mmHg
Melting Point	melting at 216°
Molecular Formula	C₂₀H₂₄O₉
Molecular Weight	408.399
Flash Point	225.4±25.0 °C
Exact Mass	408.142029
PSA	138.82000
LogP	-0.66
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.651
InChIKey	HXCGUCZXPFBNRD-DNLMCPORSA-N
SMILES	CC(C)(OC1OC(CO)C(O)C(O)C1O)C1Cc2cc3ccc(=O)oc3cc2O1

Safety Information

Safety Phrases	24/25
HS Code	29389090

Synonyms

2-(7-Oxo-2,3-dihydro-7H-furo[3,2-g]chromen-3-yl)-2-propanyl β-D-glucopyranoside

2-(7-Oxo-2,3-dihydro-7H-furo[3,2-g]chromen-3-yl)propan-2-yl β-D-glucopyranoside

2-[1-(b-D-Glucopyranosyloxy)-1-methylethyl]-2,3-dihydro-7H-furo[3,2-g][1]benzopyran-7-one

7H-Furo[3,2-g][1]benzopyran-7-one, 3-[1-(β-D-glucopyranosyloxy)-1-methylethyl]-2,3-dihydro-

Nodakenetin Glucoside

Recommended......