CAS 78355-50-7|BAM-3200

Introduction:Basic information about CAS 78355-50-7|BAM-3200, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameBAM-3200
CAS Number78355-50-7Molecular Weight3156.60000
Density/Boiling Point/
Molecular FormulaC147H207N41O34S2Melting Point/
MSDS/Flash Point/

Names

NameBAM-3200
SynonymMore Synonyms

BAM-3200 BiologicalActivity

DescriptionPeptide E is a potent kappa opiate receptor agonist. Peptide E has opiate receptor binding activity with IC50 value of 0.39 μM. Peptide E can be used for the research of central nervous system[1][2].
Related CatalogSignaling Pathways >>GPCR/G Protein >>Opioid ReceptorSignaling Pathways >>Neuronal Signaling >>Opioid ReceptorResearch Areas >>Neurological Disease
In VitroPeptide E 具有阿片受体结合活性,IC50 值为 0.39 μM[1]。
References

[1]. E P Heimer, et al. Synthesis of adrenal peptide E and some of its biological activities. Arch Biochem Biophys. 1983 Sep;225(2):518-24.  

[2]. R Quirion, et al. Peptide E and other proenkephalin-derived peptides are potent kappa opiate receptor agonists. Peptides. 1983 Jul-Aug;4(4):445-9.  

Chemical & Physical Properties

Molecular FormulaC147H207N41O34S2
Molecular Weight3156.60000
Exact Mass3154.52000
PSA1287.11000
LogP9.26360
InChIKeyPCFGFYKGPMQDBX-FEKONODYSA-N
SMILESCSCCC(NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)C(N)Cc1ccc(O)cc1)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(=O)NCC(=O)NC(CCCNC(=N)N)C(=O)N1CCCC1C(=O)NC(CCC(=O)O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCC(N)=O)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NC(CC(C)C)C(=O)O)C(C)C

Synonyms

chembl506884
Peptide E proenkephalin
Peptide E (ox adrenal medulla)
Peptide E
Proenkephalin peptide E
Opioid peptide E
Peptide E (adrenal medulla)
YGGFMRRVGRPEWWMDYQKRYGGFL
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