CAS 4454-05-1|(2R)-2-Methoxy-3,4-dihydro-2H-pyran

Introduction：Basic information about CAS 4454-05-1|(2R)-2-Methoxy-3,4-dihydro-2H-pyran, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Synonyms

Common Name	(2R)-2-Methoxy-3,4-dihydro-2H-pyran
CAS Number	4454-05-1	Molecular Weight	114.142
Density	1.0±0.1 g/cm3	Boiling Point	149.3±39.0 °C at 760 mmHg
Molecular Formula	C₆H₁₀O₂	Melting Point	/
MSDS	/	Flash Point	16.7±0.0 °C

Names

Name	3,4-Dihydro-2-Methoxy-2H-Pyran
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.0±0.1 g/cm3
Boiling Point	149.3±39.0 °C at 760 mmHg
Molecular Formula	C₆H₁₀O₂
Molecular Weight	114.142
Flash Point	16.7±0.0 °C
Exact Mass	114.068077
PSA	18.46000
LogP	-0.09
Vapour Pressure	5.1±0.3 mmHg at 25°C
Index of Refraction	1.451
InChIKey	XCYWUZHUTJDTGS-UHFFFAOYSA-N
SMILES	COC1CCC=CO1
Storage condition	Flammables area

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UP7900000

CHEMICAL NAME :: 2H-Pyran, 3,4-dihydro-2-methoxy-

CAS REGISTRY NUMBER :: 4454-05-1

BEILSTEIN REFERENCE NO. :: 0107274

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C6-H10-O2

MOLECULAR WEIGHT :: 114.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 30,545,1988

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 30,545,1988 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1410 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - other changes

REFERENCE :: VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 30,545,1988

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8044 ppm/1H

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - pleural effusion

REFERENCE :: VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 30,545,1988

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 4920 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Lungs, Thorax, or Respiration - dyspnea Skin and Appendages - dermatitis, other (after systemic exposure)

REFERENCE :: VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 30,545,1988

Safety Information

Hazard Codes	F:Highlyflammable;Xn:Harmful;
Risk Phrases	R11;R22
Safety Phrases	S9-S33-S16-S36-S26
RIDADR	1993
RTECS	UP7900000
Packaging Group	II
Hazard Class	3
HS Code	2932999099

Customs

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

2-Methoxy-3,4-dihydro-2H-pyran

3,4-Dihydro-2-Methoxy-2H-pyran

MFCD00006560

(2R)-2-Methoxy-3,4-dihydro-2H-pyran

2H-Pyran, 3,4-dihydro-2-methoxy-, (2R)-

EINECS 224-698-3

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