CAS 316-15-4|Bucricaine

CHEMICAL IDENTIFICATION

RTECS NUMBER :

AR9534000

CHEMICAL NAME :

Acridine, 1,2,3,4-tetrahydro-9-butylamino-

CAS REGISTRY NUMBER :

316-15-4

BEILSTEIN REFERENCE NO. :

0481616

LAST UPDATED :

199803

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C17-H22-N2

MOLECULAR WEIGHT :

254.41

WISWESSER LINE NOTATION :

T C666 BNT&&J IM4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

50 mg/kg

TOXIC EFFECTS :

Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :

JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 9,483,1966

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Mammal - species unspecified

DOSE/DURATION :

20 mg/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - analgesia

REFERENCE :

PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 5,654,1971