CAS 160295-81-8|MAGE-3 (271-279)

Introduction:Basic information about CAS 160295-81-8|MAGE-3 (271-279), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameMAGE-3 (271-279)
CAS Number160295-81-8Molecular Weight1058.276
Density1.4±0.1 g/cm3Boiling Point/
Molecular FormulaC53H79N13O10Melting Point/
MSDS/Flash Point/

Names

Name(2R)-2-amino-3-(1H-imidazol-5-yl)propan-1-ol
SynonymMore Synonyms

MAGE-3 (271-279) BiologicalActivity

DescriptionMAGE-3 (271-279) is a 271-279 residue peptide derived from melanoma antigens encoded by MAGE-3. MAGE-3 is a cytolytic T lymphocyte (CTL)-defined MAGE-3 protein associated with the human leukocyte antigen (HLA)-A2 molecule. MAGE-3 is overexpressed in different human tumor types, including malignant melanoma, but not by normal tissues except for testis and placenta[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Others >>Others
References

[1]. J Herman, et al. A peptide encoded by the human MAGE3 gene and presented by HLA-B44 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE3. Immunogenetics. 1996;43(6):377-83.

Chemical & Physical Properties

Density1.4±0.1 g/cm3
Molecular FormulaC53H79N13O10
Molecular Weight1058.276
Exact Mass1057.607300
PSA365.02000
LogP4.48
Index of Refraction1.642
InChIKeyPQGCYSRGXCORLN-RJXLGPPMSA-N
SMILESCC(C)CC(NC(=O)C(N)Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N1CCCC1C(=O)NC(CCCN=C(N)N)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C(=O)O)C(C)C

Synonyms

L-Valine, L-phenylalanyl-L-leucyl-L-tryptophylglycyl-L-prolyl-N-(diaminomethylene)-L-ornithyl-L-alanyl-L-leucyl-
L-Phenylalanyl-L-leucyl-L-tryptophylglycyl-L-prolyl-N-(diaminomethylene)-L-ornithyl-L-alanyl-L-leucyl-L-valine
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