CAS 3493-13-8|5'-[[(3S)-3-AMINO-3-CARBOXYPROPYL]METHYLSULFONIO]-5'-DEOXY-ADENOSINE IO
| Common Name | 5'-[[(3S)-3-AMINO-3-CARBOXYPROPYL]METHYLSULFONIO]-5'-DEOXY-ADENOSINE IODIDE | ||
|---|---|---|---|
| CAS Number | 3493-13-8 | Molecular Weight | 526.35000 |
| Density | / | Boiling Point | / |
| Molecular Formula | C15H23IN6O5S | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | s-adenosyl-l-methionine iodide salt |
|---|---|
| Synonym | More Synonyms |
BiologicalActivity
| Description | S-(5'-Adenosyl)-L-methionine iodide (S-Adenosyl-L-methionine iodide) is an important methyl donor that is found in all living organisms[1]. |
|---|---|
| Related Catalog | Research Areas >>Metabolic Disease |
| In Vitro | By donating the methyl group, sues that involves perchloric acid extraction has beenSAM is converted into S-adenosyl-L-homocysteine reported by She et al. Separation of SAM and (SAH)[1]. |
| References | [1]. W Wang, et al. Reversed-phase high-performance liquid chromatography procedure for the simultaneous determination of S-adenosyl-L-methionine and S-adenosyl-L-homocysteine in mouse liver and the effect of methionine on their concentrations. J Chromatogr B Biomed Sci Appl. 2001 Oct 5;762(1):59-65. |
Chemical & Physical Properties
| Molecular Formula | C15H23IN6O5S |
|---|---|
| Molecular Weight | 526.35000 |
| Exact Mass | 526.05000 |
| PSA | 207.93000 |
| InChIKey | XQMWYLXPEGFCFT-XKGORWRGSA-N |
| SMILES | C[S+](CCC(N)C(=O)O)CC1OC(n2cnc3c(N)ncnc32)C(O)C1O.[I-] |
| Storage condition | −20°C |
| Water Solubility | H2O: 100 mg/mL |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H317 |
| Precautionary Statements | P280 |
| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles7
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| Structure and reaction mechanism of phosphoethanolamine methyltransferase from the malaria parasite Plasmodium falciparum: an antiparasitic drug target. J. Biol. Chem. 287 , 1426-1434, (2012) In the malarial parasite Plasmodium falciparum, a multifunctional phosphoethanolamine methyltransferase (PfPMT) catalyzes the methylation of phosphoethanolamine (pEA) to phosphocholine for membrane bi... | |
| DNA methyltransferases: mechanistic models derived from kinetic analysis. Crit. Rev. Biochem. Mol. Biol. 47(2) , 97-193, (2012) The sequence-specific transfer of methyl groups from donor S-adenosyl-L-methionine (AdoMet) to certain positions of DNA-adenine or -cytosine residues by DNA methyltransferases (MTases) is a major form... |
Synonyms
| EINECS 222-486-5 |
| SAM iodide salt |
| S-(5'-ADENOSYL)-L-METHIONINE IODIDE |
| S-ADENOSYL METHIONINE IODIDE SALT |
| adomet |
| MFCD00043192 |
| S-(5'-deoxy-5'-adenosyl)methionine iodide |
| S-adenosylmethionine |
| SAM-E IODIDE SALT |
| AdoMet,SAM |
| S-adenosyl-L-methionine iodide |
| S-ADENOSYLMETHIONINE IODIDE |
| S-adenosylmethione |
