CAS 2545-00-8|(+)-Afzelechin

Introduction：Basic information about CAS 2545-00-8|(+)-Afzelechin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. (+)-Afzelechin BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	(+)-Afzelechin
CAS Number	2545-00-8	Molecular Weight	274.269
Density	1.5±0.1 g/cm3	Boiling Point	583.4±50.0 °C at 760 mmHg
Molecular Formula	C₁₅H₁₄O₅	Melting Point	/
MSDS	/	Flash Point	306.6±30.1 °C

Names

Name	afzelechin
Synonym	More Synonyms

(+)-Afzelechin BiologicalActivity

Description	(+)-Afzelechin, isolated from rhizomes of Bergenia ligulata, is an alpha-glucosidase activity inhibitor with an ID50 (50% inhibition dose) value of 0.13 mM. (+)-Afzelechin can delay the absorption of carbohydrates in food to suppress postprandial hyperglycemia and hyperinsulinemia[1].
Related Catalog	Research Areas >>Metabolic Disease
Target	ID50: 0.13 mM (alpha-glucosidase)[1]
References	[1]. Junichi Saijyo, et al. Alpha-glucosidase Inhibitor From Bergenia Ligulata. J Oleo Sci. 2008;57(8):431-5.

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	583.4±50.0 °C at 760 mmHg
Molecular Formula	C₁₅H₁₄O₅
Molecular Weight	274.269
Flash Point	306.6±30.1 °C
Exact Mass	274.084137
PSA	90.15000
LogP	1.09
Vapour Pressure	0.0±1.7 mmHg at 25°C
Index of Refraction	1.709
InChIKey	RSYUFYQTACJFML-DZGCQCFKSA-N
SMILES	Oc1ccc(C2Oc3cc(O)cc(O)c3CC2O)cc1

Safety Information

Hazard Codes	Xi

Synonyms

(2R,3R)-2-(4-Hydroxyphenyl)-3,5,7-chromanetriol

(-)-epiafzelechin

2H-1-Benzopyran-3,5,7-triol, 3,4-dihydro-2-(4-hydroxyphenyl)-, (2R,3R)-

Afzelechin

2H-1-Benzopyran-3,5,7-triol, 3,4-dihydro-2-(4-hydroxyphenyl)-, (2R,3S)-

(2R,3R)-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol

epi-Afzelechin

3,5,7,4'-Tetrahydroxyflavan

(2R,3S)-2-(4-Hydroxyphenyl)-3,5,7-chromanetriol

2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol

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