Introduction：Basic information about CAS 3614-47-9|Hydracarbazine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Hydracarbazine |
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| CAS Number | 3614-47-9 | Molecular Weight | 153.14200 |
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| Density | 1.513g/cm3 | Boiling Point | 549.1ºC at 760mmHg |
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| Molecular Formula | C5H7N5O | Melting Point | / |
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| MSDS | / | Flash Point | 285.9ºC |
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Names
| Name | 6-hydrazinylpyridazine-3-carboxamide |
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| Synonym | More Synonyms |
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Hydracarbazine BiologicalActivity
| Description | Hydracarbazine is a pyridazine. Hydracarbazine can effectively lower blood pressure, it can be used for the research of high blood pressure[1][2]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>Others |
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| In Vivo | Hydracarbazine (1-4 mg/kg; i.v. once) induced in the dog, cat and rabbit hypotension by peripheral vasodilation, showed no inhibitory action on vasomotor centers and decreased the hypertensive effects of adrenaline, noradrenaline, 5-hydroxytryptamine, pituitrin, and splanchnic nerve stimulation[1]. Hydracarbazine (15-18 mg/kg; p.o. once daily) prevents the increased blood pressure and heart rate, reduces the renal histol and reduces the hypertensive syndrome with a combination of pempidine in high arterial pressure rats[2]. |
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| References | [1]. Schmitt H, et al. Pharmacological study of a new hypotensor with a long duration of action: 1-hydrazino-4-carboxamidopyridazine (1325). Journal de Physiologie. 1992 52:525-36. [2]. Ghaye-Roquet J, et al. [Prevention of experimental hypertension in the rat by prolonged administration of a combination of antihypertensive agents]. Arch Int Pharmacodyn Ther. 1967 Mar;166(1):65-78. |
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Chemical & Physical Properties
| Density | 1.513g/cm3 |
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| Boiling Point | 549.1ºC at 760mmHg |
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| Molecular Formula | C5H7N5O |
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| Molecular Weight | 153.14200 |
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| Flash Point | 285.9ºC |
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| Exact Mass | 153.06500 |
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| PSA | 110.15000 |
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| Index of Refraction | 1.717 |
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| InChIKey | WRYZEGZNBYOMLE-UHFFFAOYSA-N |
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| SMILES | NNc1ccc(C(N)=O)nn1 |
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Safety Information
Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 3-Hydrazino-6-carbamoyl-pyridazin |
| 6-hydrazinopyridazine-3-carboxamide |
| 6-Hydrazino-pyridazin-3-carbonsaeure-amid |
| Hidracarbazina |
| 6-hydrazino-pyridazine-3-carboxylic acid amide |
| UNII-6CTK2FB9QM |
| TH-2151 |
| Hydracarbazine |
| Hydracarbazinum |
| Hydracarbazine [INN:DCF] |
| 3-carbamoyl-6-pyridazinylhydrazine |
