CAS 2591-86-8|Formylpiperidine

Introduction：Basic information about CAS 2591-86-8|Formylpiperidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles14
7. Synonyms

Common Name	Formylpiperidine
CAS Number	2591-86-8	Molecular Weight	113.158
Density	1.1±0.1 g/cm3	Boiling Point	222.5±9.0 °C at 760 mmHg
Molecular Formula	C₆H₁₁NO	Melting Point	-31 °C
MSDS	ChineseUSA	Flash Point	91.7±0.0 °C
Symbol	GHS06	Signal Word	Danger

Names

Name	N-Formylpiperidine
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	222.5±9.0 °C at 760 mmHg
Melting Point	-31 °C
Molecular Formula	C₆H₁₁NO
Molecular Weight	113.158
Flash Point	91.7±0.0 °C
Exact Mass	113.084061
PSA	20.31000
LogP	0.24
Vapour Pressure	0.1±0.4 mmHg at 25°C
Index of Refraction	1.551
InChIKey	FEWLNYSYJNLUOO-UHFFFAOYSA-N
SMILES	O=CN1CCCCC1
Water Solubility	freely soluble

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TN0380000

CHEMICAL NAME :: Piperidine, 1-formyl-

CAS REGISTRY NUMBER :: 2591-86-8

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C6-H11-N-O

MOLECULAR WEIGHT :: 113.18

WISWESSER LINE NOTATION :: T6NTJ AVH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0534369 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 870 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0534315

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 840 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0534315

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BDCGAS Berichte der Deutschen Chemischen Gesellschaft. (Leipzig, Ger. Dem. Rep.) V.1-61, 1868-1928. For publisher information, see CHBEAM. Volume(issue)/page/year: 34,2408,1901 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 6600 mg/kg

SEX/DURATION :: female 6-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 18,96,1992

Safety Information

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H302-H311-H315-H319-H335
Precautionary Statements	P261-P280-P305 + P351 + P338-P312
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn:Harmful;
Risk Phrases	R21/22
Safety Phrases	S26-S36/37
RIDADR	UN 2810 6.1/PG 3
WGK Germany	3
RTECS	TN0380000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	29333999

Customs

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles14

The small GTPase ROP10 of Medicago truncatula is required for both tip growth of root hairs and nod factor-induced root hair deformation.

Plant Cell 27 , 806-22, (2015)

Rhizobia preferentially enter legume root hairs via infection threads, after which root hairs undergo tip swelling, branching, and curling. However, the mechanisms underlying such root hair deformatio...

Binding of formamides to liver alcohol dehydrogenase.

Biochemistry 36(12) , 3522-7, (1997)

Amides are analogs of aldehydes and potent inhibitors of liver alcohol dehydrogenases. They can be used for structural studies and for inhibiting the metabolism of alcohols that form toxic products. W...

Uncompetitive inhibitors of alcohol dehydrogenases.

Adv. Exp. Med. Biol. 463 , 295-303, (1999)

Synonyms

1-formylpiperidine

1-formyl-piperidin

1-Piperidinecarboxaldehyde

Piperidine-1-carboxaldehyde

N-Formylpiperidine

EINECS 219-986-0

Formylpiperidine

Piperidin-1-carbaldehyd

N-formyl piperidine

1-Piperidinecarbaldehyde

Piperidinoformamide

MFCD00006483

N-Formylpiperidin

nfp

piperidine-1-carbaldehyde

N-Formylpiperdine

Piperidine, 1-formyl-

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