Introduction：Basic information about CAS 13392-28-4|Rimantadine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Rimantadine |
|---|
| CAS Number | 13392-28-4 | Molecular Weight | 179.30 |
|---|
| Density | 1.033 | Boiling Point | 248ºC |
|---|
| Molecular Formula | C12H21N | Melting Point | 375°C(lit.) |
|---|
| MSDS | / | Flash Point | 99ºC |
|---|
Names
| Name | 1-(1-adamantyl)ethanamine |
|---|
| Synonym | More Synonyms |
|---|
Rimantadine BiologicalActivity
| Description | Rimantadine (Flumadine) is an anti-influenza virus drug.Target: Influenza Virusrimantadine are oral antiviral drugs useful in the prophylaxis and treatment of influenza A virus infections. rimantadine has prophylactic efficacy comparable to amantadine but lower potential for causing adverse effects [1]. double-blind study of children with influenza-like illness. 37 received rimantadine for five days. Of the total 37 children in the rimantadine group, 27% were found to have resistant isolated compared with 6% in the total group receiving acetaminophen (P < .04). Furthermore, the mean inhibitory concentration of rimantadine increased with time in the rimantadine group (r = .4, P = .002) [2]. |
|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>Influenza VirusResearch Areas >>Infection |
|---|
| References | [1]. Tominack, R.L. and F.G. Hayden, Rimantadine hydrochloride and amantadine hydrochloride use in influenza A virus infections. Infect Dis Clin North Am, 1987. 1(2): p. 459-78. [2]. Hall, C.B., et al., Children with influenza A infection: treatment with rimantadine. Pediatrics, 1987. 80(2): p. 275-82. |
|---|
Chemical & Physical Properties
| Density | 1.033 |
|---|
| Boiling Point | 248ºC |
|---|
| Melting Point | 375°C(lit.) |
|---|
| Molecular Formula | C12H21N |
|---|
| Molecular Weight | 179.30 |
|---|
| Flash Point | 99ºC |
|---|
| PSA | 26.02000 |
|---|
| LogP | 4.05230 |
|---|
| Vapour Pressure | 0.0249mmHg at 25°C |
|---|
| Index of Refraction | 1.539 |
|---|
| InChIKey | UBCHPRBFMUDMNC-UHFFFAOYSA-N |
|---|
| SMILES | CC(N)C12CC3CC(CC(C3)C1)C2 |
|---|
| Storage condition | -20°C |
|---|
Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- AU4716000
- CHEMICAL NAME :
- 1-Adamantanemethylamine, alpha-methyl-
- CAS REGISTRY NUMBER :
- 13392-28-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C12-H21-N
- MOLECULAR WEIGHT :
- 179.34
|
Safety Information
| Hazard Codes | Xn |
|---|
| HS Code | 2921300090 |
|---|
Customs
| HS Code | 2921300090 |
|---|
| Summary | 2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
|---|
Synonyms
| 1-adamantanemethylamine |
| tricyclo[3.3.1.1]decane-1-methanamine, α-methyl-, hydrochloride |
| a-Methyltricyclo[3.3.1.13,7]decane-1-methanamine Hydrochloride |
| Remantadine |
| Meradan |
| α-Methyl-1-adamantanemethylamine hydrochloride |
| UNII:JEI07OOS8Y |
| [1-(1-Adamantyl)ethyl]amine hydrochloride |
| Rimant |
| MFCD03265511 |
| 1-tricyclo[3.3.1.1]déc-1-yléthanamine chlorhydrate |
| 1-(Adamantan-1-yl)ethanamine hydrochloride (1:1) |
| Roflual |
| Rimantadinum |
| 1-(tricyclo[3.3.1.1]dec-1-yl)ethanamine hydrochloride (1:1) |
| Tricyclo[3.3.1.1]decane-1-methanamine, α-methyl-, hydrochloride (1:1) |
| Flumadine |
| a-Methyl-1-adamantanemethylamine Hydrochloride |
| 1-Tricyclo[3.3.1.1]dec-1-ylethanaminhydrochlorid |
| Rimantadina |
| Rimantadine |
| Rimantadine Hydrochloride |
| 1-tricyclo[3.3.1.1]dec-1-ylethanamine hydrochloride |
| Riamantadine |
| Remantadine hydrochloride |
