CAS 1824-81-3|2-Amino-6-picoline

Introduction：Basic information about CAS 1824-81-3|2-Amino-6-picoline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles1
7. Synonyms

Common Name	2-Amino-6-picoline
CAS Number	1824-81-3	Molecular Weight	108.141
Density	1.1±0.1 g/cm3	Boiling Point	208.5±0.0 °C at 760 mmHg
Molecular Formula	C₆H₈N₂	Melting Point	40-44 °C(lit.)
MSDS	ChineseUSA	Flash Point	103.3±0.0 °C
Symbol	GHS06	Signal Word	Danger

Names

Name	6-methylpyridin-2-amine
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	208.5±0.0 °C at 760 mmHg
Melting Point	40-44 °C(lit.)
Molecular Formula	C₆H₈N₂
Molecular Weight	108.141
Flash Point	103.3±0.0 °C
Exact Mass	108.068748
PSA	38.91000
LogP	1.08
Vapour Pressure	0.2±0.4 mmHg at 25°C
Index of Refraction	1.574
InChIKey	QUXLCYFNVNNRBE-UHFFFAOYSA-N
SMILES	Cc1cccc(N)n1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: US1885000

CHEMICAL NAME :: Pyridine, 2-amino-6-methyl-

CAS REGISTRY NUMBER :: 1824-81-3

BEILSTEIN REFERENCE NO. :: 0107048

LAST UPDATED :: 199710

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C6-H8-N2

MOLECULAR WEIGHT :: 108.16

WISWESSER LINE NOTATION :: T6NJ BZ F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,841,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 52 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: AJEBAK Australian Journal of Experimental Biology and Medical Science. (Adelaide, S.A., Australia) V.1-64, 1924-86. Volume(issue)/page/year: 36,491,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 18 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00148

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,841,1986

Safety Information

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H301-H310-H315-H319-H335
Precautionary Statements	P261-P280-P301 + P310-P302 + P350-P305 + P351 + P338-P310
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T:Toxic
Risk Phrases	R24/25;R36/37/38
Safety Phrases	S26-S36/37/39-S45-S37/39-S28A
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	US1885000
Packaging Group	II
Hazard Class	6.1
HS Code	29333999

Customs

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles1

New mixed ligand zinc(II) complexes based on the antiepileptic drug sodium valproate and bioactive nitrogen-donor ligands. Synthesis, structure and biological properties.

Eur. J. Med. Chem. 82 , 152-63, (2014)

Starting from the precursor [Zinc Valproate complex] (1), new mixed ligand zinc(II) complexes of valproic acid and nitrogen-based ligands, formulating as, [Zn(valp)22,9-dmphen] (2), [Zn2(valp)4(quin)2...

Synonyms

6-Methyl-2-aminopyridine

2-amino-6-Me-pyridine

2-Picoline,6-amino

6-Methyl-pyridin-2-ylamine

2-Amino-6-methylpyridine

2-Pyridinamine,6-methyl

6-Methyl-2-pyridylamine

MFCD00006331

6-Methylpyridin-2-amin

2-amino-6-methyl-pyridine

2-Pyridinamine, 6-methyl-

6-Methyl-2-pyridinamine

6-MePy-2-NH2

6-methylpyridin-2-amine

6-Amino-2-picoline

2-Amino-6-picoline

EINECS 217-360-1

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