CAS 13292-22-3|3-Formyl Rifamycin

Introduction:Basic information about CAS 13292-22-3|3-Formyl Rifamycin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name3-Formyl Rifamycin
CAS Number13292-22-3Molecular Weight725.779
Density1.4±0.1 g/cm3Boiling Point855.4±65.0 °C at 760 mmHg
Molecular FormulaC38H47NO13Melting Point182-184°C
MSDS/Flash Point471.1±34.3 °C

Names

Name3-Formyl Rifamycin
SynonymMore Synonyms

3-Formyl Rifamycin BiologicalActivity

Description3-Formyl rifamycin is an intermediate of Rifampicin.
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others

Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point855.4±65.0 °C at 760 mmHg
Melting Point182-184°C
Molecular FormulaC38H47NO13
Molecular Weight725.779
Flash Point471.1±34.3 °C
Exact Mass725.304749
PSA218.38000
LogP2.85
Vapour Pressure0.0±0.3 mmHg at 25°C
Index of Refraction1.633
InChIKeyBBNQHOMJRFAQBN-UPZFVJMDSA-N
SMILESCOC1C=COC2(C)Oc3c(C)c(O)c4c(O)c(c(C=O)c(O)c4c3C2=O)NC(=O)C(C)=CC=CC(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C
Storage condition-20°C Freezer, Under Inert Atmosphere

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KD1600000
CHEMICAL NAME :
2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-8-carboxaldehyd e, 1,2-dihydro-5, 6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,2 2-heptamethyl-1,11-di oxo-, 21-acetate
CAS REGISTRY NUMBER :
13292-22-3
LAST UPDATED :
199703
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C38-H47-N-O13
MOLECULAR WEIGHT :
725.86

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
907 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4002754
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
416 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4002754
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
299 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
38KLAC "Structure-Activity Relationship among the Semisynthetic Antibiotics," Perlman, D., ed., New York, Academic Press, 1977 Volume(issue)/page/year: -,531,1977

Synonyms

(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-26-Formyl-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1.0]triaconta-1( 
29),2,4,9,19,21,25,27-octaen-13-yl acetate
(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-26-Formyl-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1.0]triaconta-1(28),2,4,9,19,21,25(29),26-octaen-13-yl acetate
2,7-(Epoxy[1,11,13]pentadecatrienoimino)naphtho[2,1-b]furan-8-carboxaldehyde, 21-(acetyloxy)-1,2-dihydro-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-, (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-
3-Formylrifamycin
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