CAS 1667-11-4|4-(Chloromethyl)biphenyl

Introduction：Basic information about CAS 1667-11-4|4-(Chloromethyl)biphenyl, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Customs
6. Articles25
7. Synonyms

Common Name	4-(Chloromethyl)biphenyl
CAS Number	1667-11-4	Molecular Weight	202.679
Density	1.1±0.1 g/cm3	Boiling Point	322.4±21.0 °C at 760 mmHg
Molecular Formula	C₁₃H₁₁Cl	Melting Point	70-73 °C(lit.)
MSDS	ChineseUSA	Flash Point	143.2±14.7 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	4-Biphenylmethyl chloride
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	322.4±21.0 °C at 760 mmHg
Melting Point	70-73 °C(lit.)
Molecular Formula	C₁₃H₁₁Cl
Molecular Weight	202.679
Flash Point	143.2±14.7 °C
Exact Mass	202.054932
LogP	4.24
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.579
InChIKey	HLQZCRVEEQKNMS-UHFFFAOYSA-N
SMILES	ClCc1ccc(-c2ccccc2)cc1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DV2087000

CHEMICAL NAME :: Biphenyl, 4-(chloromethyl)-

CAS REGISTRY NUMBER :: 1667-11-4

BEILSTEIN REFERENCE NO. :: 1863327

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C13-H11-Cl

MOLECULAR WEIGHT :: 202.69

WISWESSER LINE NOTATION :: G1R DR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 250 mg/kg

SEX/DURATION :: male 5 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 2500 mg/kg

SEX/DURATION :: male 5 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

MUTATION DATA

TYPE OF TEST :: Morphological transformation

TEST SYSTEM :: Rodent - hamster Kidney

DOSE/DURATION :: 2500 ug/L

REFERENCE :: CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 2,33,1981

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	DV2087000
HS Code	2903999090

Customs

HS Code	2903999090
Summary	2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles25

The biological activity of 4-chloromethylbiphenyl, benzyl chloride and 4-hydroxymethylbiphenyl in 4 short-term tests for carcinogenicity. A report of an individual study in the UKEMS genotoxicity trial 1981.

Mutat. Res. 119(2) , 121-33, (1983)

4-Chloromethylbiphenyl (4CMB), benzyl chloride (BC) and 4-hydroxymethyl-biphenyl (4HMB) were tested for biological activity in the following assays: (i) the Salmonella/microsome assay; (ii) a bacteria...

The use of cultured mammalian cells the UKEMS collaborative genotoxicity trial (1981).

Mutat. Res. 100(1-4) , 271-6, (1982)

The effects of 4CMB, 4HMB and BC in the micronucleus test.

Mutat. Res. 100(1-4) , 353-6, (1982)

Synonyms

4-(Chloromethyl)-1,1'-biphenyl

4-(Chloromethyl)biphenyl

1-(chloromethyl)-4-phenylbenzene

1,1'-Biphenyl, 4-(chloromethyl)-

EINECS 216-786-5

Biphenyl, 4- (chloromethyl)-

MFCD00000917

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