CAS 137181-56-7|Systemin

Introduction:Basic information about CAS 137181-56-7|Systemin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameSystemin
CAS Number137181-56-7Molecular Weight2010.28000
Density/Boiling Point/
Molecular FormulaC85H144N26O28SMelting Point/
MSDS/Flash Point/

Names

Namesystemin
SynonymMore Synonyms

Systemin BiologicalActivity

DescriptionSystemin, an 18-amino acid polypeptide, has been isolated from tomato leaves that is a powerful inducer of over 15 defensive genes. Sequence: Ala-Val-Gln-Ser-Lys-Pro-Pro-Ser-Lys-Arg-Asp-Pro-Pro-Lys-Met-Gln-Thr-Asp.
Related CatalogSignaling Pathways >>Others >>OthersNatural Products >>OthersResearch Areas >>OthersPeptides
In VitroSystemin is readily transported from wound sites and is considered to be the primary systemic signal.The signal transduction pathway that mediates Systemin signaling involves linolenic acid release from membranes and subsequent conversion to jasmonic acid, a potent activator of defense gene transcription. The pathway exhibits analogies to arachidonic acid/prostaglandin signaling in animals that leads to inflammatory and acute phase responses[1]. Systemin, an 18-amino-acid peptide signal. Systemin is cleaved from the C-terminal region of a 200-amino acid precursor protein called proSystemin. Following the cloning of proSystemin gene, which represents a single locus in the tomato genome, several lines of genetic evidence indicate that Systemin acts as an upstream component of wound-induced signaling cascades leading to defense gene expression[2].
References

[1]. Ryan CA, et al. Systemin: a polypeptide signal for plant defensive genes. Annu Rev Cell Dev Biol. 1998;14:1-17.

[2]. Sun JQ, et al. Systemin/Jasmonate-mediated systemic defense signaling in tomato. Mol Plant. 2011 Jul;4(4):607-15.

Chemical & Physical Properties

Molecular FormulaC85H144N26O28S
Molecular Weight2010.28000
Exact Mass2009.04000
PSA909.59000
Storage condition2-8℃

Synonyms

ala-val-glu-ser-lys-pro-pro-ser-lys-arg-asp-pro-pro-lys-met-glu-thr-asp
h2n-avqskppskrdppkmqtd-oh
h-ala-val-gln-ser-lys-pro-pro-ser-lys-arg-asp-pro-pro-lys-met-gln-thr-asp-oh
ala-val-gln-ser-lys-pro-pro-ser-lys-arg-asp-pro-pro-lys-met-gln-thr-asp
avqskppskrdppkmqtd
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