Introduction：Basic information about CAS 13877-76-4|7H-Pyrazolo[4,3-d]pyrimidin-7-one,1,6-dihydro-3-b-D-ribofuranosyl-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 7H-Pyrazolo[4,3-d]pyrimidin-7-one,1,6-dihydro-3-b-D-ribofuranosyl- |
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| CAS Number | 13877-76-4 | Molecular Weight | 268.22600 |
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| Density | 2.18g/cm3 | Boiling Point | 683.2ºC at 760mmHg |
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| Molecular Formula | C10H12N4O5 | Melting Point | / |
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| MSDS | / | Flash Point | 367ºC |
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Names
| Name | formycin B |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 2.18g/cm3 |
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| Boiling Point | 683.2ºC at 760mmHg |
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| Molecular Formula | C10H12N4O5 |
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| Molecular Weight | 268.22600 |
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| Flash Point | 367ºC |
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| Exact Mass | 268.08100 |
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| PSA | 144.35000 |
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| Vapour Pressure | 1.34E-19mmHg at 25°C |
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| Index of Refraction | 1.921 |
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| InChIKey | MTCJZZBQNCXKAP-UHFFFAOYSA-N |
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| SMILES | O=c1[nH]cnc2c(C3OC(CO)C(O)C3O)[nH]nc12 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- UR0800000
- CHEMICAL NAME :
- 7H-Pyrazolo(4,3-d)pyrimidin-7-one, 1,4-dihydro-3-beta-D-ribofuranosyl-
- CAS REGISTRY NUMBER :
- 13877-76-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C10-H12-N4-O5
- MOLECULAR WEIGHT :
- 268.26
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4 gm/kg/10D-I
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
MUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 10 umol/L
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 30,2651,1981
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Synonyms
| FORMYCIN B |
| LAURUSIN |
| D-Ribitol, 1,4-anhydro-1-C-(6,7-dihydro-7-oxo-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-, (S)- |
| OHYAMYCIN |
