Introduction：Basic information about CAS 31721-94-5|5,7-Dihydroxychromone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5,7-Dihydroxychromone |
|---|
| CAS Number | 31721-94-5 | Molecular Weight | 178.141 |
|---|
| Density | 1.6±0.1 g/cm3 | Boiling Point | 399.4±42.0 °C at 760 mmHg |
|---|
| Molecular Formula | C9H6O4 | Melting Point | 232-273℃ |
|---|
| MSDS | / | Flash Point | 170.8±21.4 °C |
|---|
Names
| Name | 5,7-dihydroxychromen-4-one |
|---|
| Synonym | More Synonyms |
|---|
5,7-Dihydroxychromone BiologicalActivity
| Description | 5,7-Dihydroxychromone, the extract of Cudrania tricuspidata, activates Nrf2/ARE signal and exerts neuroprotective effects against 6-hydroxydopamine (6-OHDA)-induced oxidative stress and apoptosis. 5,7-Dihydroxychromone inhibits the expression of activated caspase-3 and caspase-9 and cleaved PARP in 6-OHDA-induced SH-SY5Y cells[1]. |
|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>ArenavirusSignaling Pathways >>NF-κB >>Keap1-Nrf2Signaling Pathways >>Epigenetics >>PARPSignaling Pathways >>Apoptosis >>CaspaseResearch Areas >>Neurological DiseaseSignaling Pathways >>Cell Cycle/DNA Damage >>PARP |
|---|
| Target | Nrf2 Caspase-3 Caspase-9 PARP |
|---|
| References | [1]. Kim DW, et al. Neuroprotection against 6-OHDA-induced oxidative stress and apoptosis in SH-SY5Y cells by 5,7-Dihydroxychromone: Activation of the Nrf2/ARE pathway. Life Sci. 2015 Jun 1;130:25-30. |
|---|
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|
| Boiling Point | 399.4±42.0 °C at 760 mmHg |
|---|
| Melting Point | 232-273℃ |
|---|
| Molecular Formula | C9H6O4 |
|---|
| Molecular Weight | 178.141 |
|---|
| Flash Point | 170.8±21.4 °C |
|---|
| Exact Mass | 178.026611 |
|---|
| PSA | 70.67000 |
|---|
| LogP | 0.54 |
|---|
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
|---|
| Index of Refraction | 1.689 |
|---|
| InChIKey | NYCXYKOXLNBYID-UHFFFAOYSA-N |
|---|
| SMILES | O=c1ccoc2cc(O)cc(O)c12 |
|---|
Safety Information
| Hazard Codes | Xi |
|---|
| HS Code | 2914400090 |
|---|
Customs
| HS Code | 2914400090 |
|---|
| Summary | 2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
|---|
Synonyms
| 4H-1-Benzopyran-4-one, 5,7-dihydroxy- |
| 5,7-dihydroxy-4H-1-benzopyran-4-one |
| 5,7-Dihydroxychromone |
| 2H-1-Benzopyran-2-one, 5,7-dihydroxy- |
| 5,7-Dihydroxy-4H-chromen-4-one |
| 5,7-Dihydroxy-2H-chromen-2-one |
| 5,7-dihydroxy-chromen-4-one |
| 5,7-Dihydroxy-chromen-4-on |
| 5,7-DIHYDROXYCOUMARIN |
