CAS 130-16-5|5-Chloro-8-hydroxyquinoline
Introduction：Basic information about CAS 130-16-5|5-Chloro-8-hydroxyquinoline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5-Chloro-8-hydroxyquinoline | ||
|---|---|---|---|
| CAS Number | 130-16-5 | Molecular Weight | 179.603 |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 348.7±22.0 °C at 760 mmHg |
| Molecular Formula | C9H6ClNO | Melting Point | 122-124 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 164.7±22.3 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 5-Chloro-8-hydroxyquinoline |
|---|---|
| Synonym | More Synonyms |
5-Chloro-8-hydroxyquinoline BiologicalActivity
| Description | Cloxiquine is an antibacterial, antifungal, antiaging and antituberculosis drug. |
|---|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>BacterialSignaling Pathways >>Anti-infection >>FungalResearch Areas >>Infection |
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 348.7±22.0 °C at 760 mmHg |
| Melting Point | 122-124 °C(lit.) |
| Molecular Formula | C9H6ClNO |
| Molecular Weight | 179.603 |
| Flash Point | 164.7±22.3 °C |
| Exact Mass | 179.013794 |
| PSA | 33.12000 |
| LogP | 3.02 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.697 |
| InChIKey | CTQMJYWDVABFRZ-UHFFFAOYSA-N |
| SMILES | Oc1ccc(Cl)c2cccnc12 |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 1200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 1 mmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 307,141,1994
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 1 mmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 307,141,1994
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | VC4590000 |
| HS Code | 2933499090 |
Customs
| HS Code | 2933499090 |
|---|---|
| Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles7
More Articles| Identifying chelators for metalloprotein inhibitors using a fragment-based approach. J. Med. Chem. 54 , 591-602, (2011) Fragment-based lead design (FBLD) has been used to identify new metal-binding groups for metalloenzyme inhibitors. When screened at 1 mM, a chelator fragment library (CFL-1.1) of 96 compounds produced... | |
| Photoluminescence and thermoanalytical studies of complexes based on 5-Cl-8-hydroxyquinoline and calix[4]arene ligands. Mater. Sci. Eng. C. Mater. Biol. Appl. 33(4) , 2213-20, (2013) A innovative 5-Cl-8-oxyquinolinepropoxycalix[4]arene ligand (2) have been prepared, exhibiting, at room temperature, blue fluorescent light emission and resulting in shift band to green fluorescent li... | |
| Poly(L-lactide) and poly(butylene succinate) immiscible blends: from electrospinning to biologically active materials. Mater. Sci. Eng. C. Mater. Biol. Appl. 41 , 119-26, (2014) For the first time the preparation of defect-free fibers from immiscible blends of high molar mass poly(lactic acid) (PLA) and poly(butylene succinate) (PBS) in the whole range of the polyester weight... |
Synonyms
| 5-Chloro-8-hydroxy quinoline |
| 5-chloroquinolin-8-ol |
| 5-Chloroquinophenol |
| cloxiquine |
| 5-Chlorooxine |
| EINECS 204-978-1 |
| 5-Chloro-8-quinolinol |
| 5-Chloro-8-hydroxyquinoline |
| 5-Chloro-quinolin-8-ol |
| 8-Quinolinol, 5-chloro- |
| Dermofungin |
| quinolin-8-ol, 5-chloro- |
| 5-Chloro-8-oxyquinoline |
| MFCD00006788 |
| 5-Chloro-8-oxychinolin |
| cloxyquin |
| 5-CHLORO-8-HYDROXY-QUINOLINE |
